RegulonDB Gene Evolutionary Conservation
Evolutionary conservation of the CytR regulatory interaction in cytR orthologous genes

In general an interaction is conserved if there is a significant overrepresentation of TFBSs in the set of orthologous promoters of the target gene. The set of orthologous promoter for cytR was scanned with the annotated matrix for CytR. In order to avoid bias due to an excessive representation of close genomes (i.e. several E. coli genomes) we masked the regulatory sequences that were too similar. Overrepresentation is calculated based on the binomial distribution, comparing the observed scores vs. the expected ones for the masked sequence set.


Ortholog predicted binding sitescytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_CytR_sites.tab
Ortholog predicted binding sites graphcytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_CytR_sites.jpg
genescytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_query_genes.tab
Query sequencecytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_query_seq.fasta
OrthologscytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_ortho_bbh.tab
ortho sequencescytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_ortho_seq.fasta
Purged sequencescytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_ortho_seq_purged.fasta
Occ sigcytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_CytR_occ_sig.tab
Occ sig graphcytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_CytR_occ_sig.jpg
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Occ freq graphcytR_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_CytR_occ_freq.jpg
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