RegulonDB RegulonDB 11.1: Gene Form
   

garL gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

garP garR garL Fur garRp garRp

Gene      
Name: garL    Texpresso search in the literature
Synonym(s): ECK3114, EG10016, b3126, yhaF
Genome position(nucleotides): 3272787 <-- 3273557
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.92
External database links:  
ASAP:
 ABE-0010276
ECHOBASE:
 EB0016
ECOLIHUB:
 garL
OU-MICROARRAY:
 b3126
STRING:
 511145.b3126
COLOMBOS: garL


Product      
Name: α-dehydro-β-deoxy-D-glucarate aldolase
Synonym(s): GarL, YhaF
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 27.384
Isoelectric point: 5.944
Motif(s):
 
Type Positions Sequence Comment
20 -> 245 QIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAELAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRS

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003824 - catalytic activity
GO:0016829 - lyase activity
GO:0046872 - metal ion binding
GO:0016830 - carbon-carbon lyase activity
GO:0016832 - aldehyde-lyase activity
GO:0008672 - 2-dehydro-3-deoxyglucarate aldolase activity
GO:0000287 - magnesium ion binding
biological_process GO:0019394 - glucarate catabolic process
GO:0046392 - galactarate catabolic process
GO:0042838 - D-glucarate catabolic process
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P23522
DIP:
 DIP-9740N
ECOCYC:
 KDGALDOL-MONOMER
ECOLIWIKI:
 b3126
INTERPRO:
 IPR017648
INTERPRO:
 IPR040442
INTERPRO:
 IPR015813
INTERPRO:
 IPR005000
MODBASE:
 P23522
PDB:
 1DXF
PDB:
 1DXE
PFAM:
 PF03328
PRIDE:
 P23522
PRODB:
 PRO_000022752
REFSEQ:
 NP_417595
SMR:
 P23522
UNIPROT:
 P23522


Operon      
Name: garPLRK-rnpB         
Operon arrangement:
Transcription unit        Promoter
rnpB
garR
garPLRK-rnpB


Transcriptional Regulation      
Display Regulation             
Activated by: FNR, CdaR
Repressed by: H-NS, Fur


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB