RegulonDB RegulonDB 10.10: Gene Form
   

flk gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

fabB yfcJ pdxB flk anti-anti-terminator anti-terminator terminator TSS_2635 TSS_2635 TSS_2634 TSS_2634 TSS_2633 TSS_2633 TSS_2632 TSS_2632 TSS_2631 TSS_2631 TSS_2630 (cluster) TSS_2630 (cluster) yfcJp2 yfcJp2 TSS_2628 TSS_2628 flKp flKp pdxBp pdxBp TSS_2627 TSS_2627 TSS_2626 TSS_2626 usgp usgp

Gene      
Name: flk    Texpresso search in the literature
Synonym(s): ECK2315, EG10229, b2321, div
Genome position(nucleotides): 2437950 --> 2438945 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.01
External database links:  
ASAP:
 ABE-0007667
ECHOBASE:
 EB0225
ECOLIHUB:
 flk
OU-MICROARRAY:
 b2321
STRING:
 511145.b2321
COLOMBOS: flk


Shine dalgarno      
Sequence: tttcaggtatAAGGATacgtaATG


Product      
Name: putative flagella assembly protein
Synonym(s): Div, Flk
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 36.668
Isoelectric point: 10.014
Motif(s):
 
Type Positions Sequence
2 -> 2 I
310 -> 330 ATRPALWILLVAIILMLVWLV

 
Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.4 - flagella
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0031224 - intrinsic component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
biological_process GO:0010468 - regulation of gene expression
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-9448N
ECOCYC:
 EG10229-MONOMER
ECOLIWIKI:
 b2321
INTERPRO:
 IPR023597
PRIDE:
 P15286
PRODB:
 PRO_000022672
REFSEQ:
 NP_416824
UNIPROT:
 P15286


Operon      
Name: flk         
Operon arrangement:
Transcription unit        Promoter
flk


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2626 2437519 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2627 2437883 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2628 2440231 reverse nd [RS-EPT-CBR] [1]
  promoter yfcJp2 2440241 reverse nd [ICWHO], [RS-EPT-CBR] [1], [2]
  promoter TSS_2630 (cluster) 2440572 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2631 2440574 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2632 2440576 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2633 2440845 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2634 2440847 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2635 2441152 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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