RegulonDB

Gene
Name:	proW
Synonym(s):	ECK2672, EG10772, b2678, osrA, proU
Genome position(nucleotides):	2806010 --> 2807074 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	58.12
External database links:

ASAP:	ABE-0008816
ECHOBASE:	EB0765
OU-MICROARRAY:	b2678
PortEco:	proW
STRING:	511145.b2678
COLOMBOS:	proW

Shine dalgarno
Sequence:	tagatcgtgaGGGGGTaaataATG

Product

Name:

glycine betaine ABC transporter membrane subunit ProW

Synonym(s):

OsrA, ProU, ProW

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

37.62

Isoelectric point:

9.677

Motif(s):

Type	Positions	Sequence
	145 -> 324	AMVTLALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLT
	163 -> 324	GLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLT
	149 -> 169	LALVLTALLFCIVIGLPLGIW
	100 -> 120	LLLGMPAPVAIIVFALIAWQI
	122 -> 142	GVGMGVATLVSLIAIGAIGAW

Classification:

Multifun Terms (GenProtEC)
		5 - cell processes --> 5.5 - adaptations --> 5.5.1 - osmotic pressure
		6 - cell structure --> 6.1 - membrane
		4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.m - ABC superfamily, membrane component
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane GO:0043190 - ATP-binding cassette (ABC) transporter complex GO:1902495 - transmembrane transporter complex
	molecular_function	GO:0005515 - protein binding GO:0005275 - amine transmembrane transporter activity GO:0015226 - carnitine transmembrane transporter activity
	biological_process	GO:0006865 - amino acid transport GO:0015837 - amine transport GO:0006972 - hyperosmotic response GO:0055085 - transmembrane transport GO:0031460 - glycine betaine transport GO:0015871 - choline transport GO:1902603 - carnitine transmembrane transport

Note(s):

Note(s): ...[more].

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

PFAM:

PRIDE:

PRODB:

PROSITE:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

proVWX

Operon arrangement:

Transcription unit	Promoter
proVWX	proVp1
proVWX	proVp2
proVWX	proVp3

Transcriptional Regulation
	Display Regulation
Activated by:	IHF
Repressed by:	H-NS

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_2992	2805036		forward	nd	[RS-EPT-CBR]	[1]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.