RegulonDB

Gene
Name:	rhaR
Synonym(s):	ECK3899, EG10842, b3906, rhaC1
Genome position(nucleotides):	4098646 --> 4099494 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	50.18
External database links:

ASAP:	ABE-0012747
CGSC:	290
ECHOBASE:	EB0835
ECOLIHUB:	rhaR
OU-MICROARRAY:	b3906
STRING:	511145.b3906
COLOMBOS:	rhaR

Shine dalgarno
Sequence:	tctggccgagGTAGCCacgGTG

Product

Name:

DNA-binding transcriptional activator RhaR

Synonym(s):

RhaR

Sequence:

Get amino acid sequence Fasta Format

Regulator Family:

AraC/XylS

Cellular location:

cytosol

Molecular weight:

32.373

Isoelectric point:

6.693

Motif(s):

Type	Positions	Sequence
	244 -> 267	ISDISTECGFEDSNYFSVVFTRET
	179 -> 277	DKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRHL
	23 -> 140	ADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFNASAGQPHWRLGSMGMAQARQVIGQLEHESSQH
	196 -> 217	DKFCDEASCSERVLRQQFRQQT
	199 -> 275	CDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWR

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
		2 - information transfer --> 2.2 - RNA related --> 2.2.2 - Transcription related
		3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level --> 3.1.2.2 - activator
		3 - regulation --> 3.3 - genetic unit regulated --> 3.3.1 - operon
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0005829 - cytosol
	molecular_function	GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0043565 - sequence-specific DNA binding
	biological_process	GO:0006351 - transcription, DNA-templated GO:0006355 - regulation of transcription, DNA-templated GO:0019299 - rhamnose metabolic process GO:0045893 - positive regulation of transcription, DNA-templated

Reference(s):

[1] Egan SM., et al., 1993
[2] Garcia-Martin C., et al., 1992
[3] Plunkett G., et al., 1993
[4] Tate CG., et al., 1992
[5] Tobin JF., et al., 1987

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PFAM:

PFAM:

PRIDE:

PRINTS:

PRODB:

PROSITE:

PROSITE:

REFSEQ:

SMART:

SMR:

UNIPROT:

Transcriptional Regulation
	Display Regulation
Activated by:	CRP, RhaR, RhaS
Undetermined regulation	RhaS

Reference(s)
[1] Egan SM., Schleif RF., 1993, A regulatory cascade in the induction of rhaBAD., J Mol Biol 234(1):87-98
[2] Garcia-Martin C., Baldoma L., Badia J., Aguilar J., 1992, Nucleotide sequence of the rhaR-sodA interval specifying rhaT in Escherichia coli., J Gen Microbiol 138(6):1109-16
[3] Plunkett G., Burland V., Daniels DL., Blattner FR., 1993, Analysis of the Escherichia coli genome. III. DNA sequence of the region from 87.2 to 89.2 minutes., Nucleic Acids Res 21(15):3391-8
[4] Tate CG., Muiry JA., Henderson PJ., 1992, Mapping, cloning, expression, and sequencing of the rhaT gene, which encodes a novel L-rhamnose-H+ transport protein in Salmonella typhimurium and Escherichia coli., J Biol Chem 267(10):6923-32
[5] Tobin JF., Schleif RF., 1987, Positive regulation of the Escherichia coli L-rhamnose operon is mediated by the products of tandemly repeated regulatory genes., J Mol Biol 196(4):789-99