RegulonDB RegulonDB 10.8: Gene Form
   

yciH gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

lapB pyrF yciH osmB pyrFp pyrFp

Gene      
Name: yciH    Texpresso search in the literature
Synonym(s): ECK1277, EG11128, b1282
Genome position(nucleotides): 1342658 --> 1342984 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
49.85
External database links:  
ASAP:
ABE-0004307
ECHOBASE:
EB1118
OU-MICROARRAY:
b1282
PortEco:
yciH
STRING:
511145.b1282
COLOMBOS: yciH


Product      
Name: putative translation factor
Synonym(s): YciH
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 11.396
Isoelectric point: 9.94
Motif(s):
 
Type Positions Sequence
32 -> 101 VVRIQRQTSGRKGKGVCLITGVDLDDAELTKLAAELKKKCGCGGAVKDGVIEIQGDKRDLLKSLLEAKGM

 

Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.3 - protein related --> 2.3.2 - translation
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
GO:0043024 - ribosomal small subunit binding
biological_process GO:0006412 - translation
GO:0006413 - translational initiation
GO:0006417 - regulation of translation
GO:0001731 - formation of translation preinitiation complex
GO:0002188 - translation reinitiation
Note(s): Note(s): ...[more].
Evidence: [HIFS] Human inference of function from sequence
[IGI] Inferred from genetic interaction
Reference(s): [1] Cort JR., et al., 1999
[2] Gagarinova A., et al., 2016
External database links:  
DIP:
DIP-11582N
DISPROT:
DP00790
ECOCYC:
EG11128-MONOMER
ECOLIWIKI:
b1282
INTERPRO:
IPR005872
INTERPRO:
IPR036877
INTERPRO:
IPR001950
MINT:
MINT-1276753
MODBASE:
P08245
PANTHER:
PTHR12789
PDB:
1D1R
PFAM:
PF01253
PRIDE:
P08245
PROSITE:
PS50296
REFSEQ:
NP_415798
SMR:
P08245
UNIPROT:
P08245


Operon      
Name: lapAB-pyrF-yciH         
Operon arrangement:
Transcription unit        Promoter
lapAB
yciSM-pyrF-yciH
lapAB
pyrF-yciH


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Cort JR., Koonin EV., Bash PA., Kennedy MA., 1999, A phylogenetic approach to target selection for structural genomics: solution structure of YciH., Nucleic Acids Res 27(20):4018-27

 [2] Gagarinova A., Stewart G., Samanfar B., Phanse S., White CA., Aoki H., Deineko V., Beloglazova N., Yakunin AF., Golshani A., Brown ED., Babu M., Emili A., 2016, Systematic Genetic Screens Reveal the Dynamic Global Functional Organization of the Bacterial Translation Machinery., Cell Rep 17(3):904-916


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