RegulonDB RegulonDB 10.9: Gene Form
   

dadA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

Gene      
Name: dadA    Texpresso search in the literature
Synonym(s): ECK1177, EG11407, b1189, dadR
Genome position(nucleotides): 1237571 --> 1238869 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
56.27
External database links:  
ASAP:
ABE-0003995
CGSC:
18433
CGSC:
884
ECHOBASE:
EB1379
ECOLIHUB:
dadA
OU-MICROARRAY:
b1189
STRING:
511145.b1189
COLOMBOS: dadA


Product      
Name: D-amino acid dehydrogenase
Synonym(s): DadA, DadR
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,inner membrane
Molecular weight: 47.607
Isoelectric point: 6.605
Motif(s):
 
Type Positions Sequence
2 -> 397 RVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKFRFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMVVRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQLLSDL
3 -> 17 VVILGSGVVGVASAW

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.3 - amino acids
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0016020 - membrane
GO:0005886 - plasma membrane
molecular_function GO:0016491 - oxidoreductase activity
GO:0008718 - D-amino-acid dehydrogenase activity
biological_process GO:0019478 - D-amino acid catabolic process
GO:0055114 - oxidation-reduction process
GO:0019480 - L-alanine oxidation to pyruvate via D-alanine
GO:0055130 - D-alanine catabolic process
Reference(s): [1] Franklin FC., et al., 1981
External database links:  
DIP:
DIP-6852N
ECOCYC:
DALADEHYDROGA-MONOMER
ECOLIWIKI:
b1189
INTERPRO:
IPR006076
INTERPRO:
IPR036188
INTERPRO:
IPR023080
MODBASE:
P0A6J5
PFAM:
PF01266
PRIDE:
P0A6J5
PRODB:
PRO_000022396
REFSEQ:
NP_415707
UNIPROT:
P0A6J5


Operon      
Name: dadAX         
Operon arrangement:
Transcription unit        Promoter
dadAX
dadAX
dadAX


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: CRP, Lrp


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1513 1236798 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_1514 1236840 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_1515 1237036 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_1516 1237229 reverse nd [RS-EPT-CBR] [2]



RegulonDB