RegulonDB RegulonDB 10.10: Gene Form
   

glmM gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ftsH glmM folP secG anti-anti-terminator anti-terminator terminator anti-anti-terminator anti-terminator terminator TSS_3484 TSS_3484 TSS_3483 TSS_3483 TSS_3482 TSS_3482 TSS_3481 TSS_3481 TSS_3480 TSS_3480 TSS_3479 TSS_3479 TSS_3478 TSS_3478 TSS_3477 TSS_3477 TSS_3476 TSS_3476 secGp2 secGp2 secGp1 secGp1 leuUp leuUp

Gene      
Name: glmM    Texpresso search in the literature
Synonym(s): ECK3165, EG11553, b3176, mrsA, yhbF
Genome position(nucleotides): 3322733 <-- 3324070 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
54.41
External database links:  
ASAP:
ABE-0010439
CGSC:
38690
ECHOBASE:
EB1514
ECOLIHUB:
glmM
OU-MICROARRAY:
b3176
STRING:
511145.b3176
COLOMBOS: glmM


Product      
Name: phosphoglucosamine mutase
Synonym(s): GlmM, MrsA, YhbF
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 47.544
Isoelectric point: 5.881
Motif(s):
 
Type Positions Sequence
162 -> 162 C
69 -> 69 A
102 -> 102 S
417 -> 417 P
2 -> 445 SNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEAALGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.3 - lipopolysaccharide --> 1.6.3.1 - O antigen
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.4 - enterobacterial common antigen (surface glycolipid)
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.7 - murein (peptidoglycan)
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.12 - amino sugar conversions
  6 - cell structure --> 6.2 - murein
  6 - cell structure --> 6.3 - surface antigens (ECA, O antigen of LPS)
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016853 - isomerase activity
GO:0046872 - metal ion binding
GO:0016868 - intramolecular transferase activity, phosphotransferases
GO:0004615 - phosphomannomutase activity
GO:0008966 - phosphoglucosamine mutase activity
GO:0000287 - magnesium ion binding
GO:0042802 - identical protein binding
biological_process GO:0005975 - carbohydrate metabolic process
GO:0009252 - peptidoglycan biosynthetic process
GO:0006048 - UDP-N-acetylglucosamine biosynthetic process
GO:0046777 - protein autophosphorylation
GO:0071704 - organic substance metabolic process
External database links:  
DIP:
DIP-10260N
ECOCYC:
PHOSGLUCOSAMINEMUT-MONOMER
ECOLIWIKI:
b3176
INTERPRO:
IPR005843
INTERPRO:
IPR005844
INTERPRO:
IPR005845
INTERPRO:
IPR005846
INTERPRO:
IPR006352
INTERPRO:
IPR016055
INTERPRO:
IPR016066
INTERPRO:
IPR036900
INTERPRO:
IPR005841
MODBASE:
P31120
PFAM:
PF02880
PFAM:
PF02879
PFAM:
PF02878
PFAM:
PF00408
PRIDE:
P31120
PRINTS:
PR00509
PRODB:
PRO_000022780
PROSITE:
PS00710
REFSEQ:
NP_417643
SMR:
P31120
UNIPROT:
P31120


Operon      
Name: folP-glmM         
Operon arrangement:
Transcription unit        Promoter
folP-glmM


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3476 3323735 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3477 3324129 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3478 3324319 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3479 3324325 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3480 3325230 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3481 3325234 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3482 3325504 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3483 3325595 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3484 3326682 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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