RegulonDB RegulonDB 11.1: Gene Form
   

moaC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

moaB moaC moaE moaD

Gene      
Name: moaC    Texpresso search in the literature
Synonym(s): ECK0772, EG11666, b0783, chlA3
Genome position(nucleotides): 818570 --> 819055
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.97
External database links:  
ASAP:
 ABE-0002673
CGSC:
 31225
ECHOBASE:
 EB1617
ECOLIHUB:
 moaC
OU-MICROARRAY:
 b0783
STRING:
 511145.b0783
COLOMBOS: moaC


Product      
Name: cyclic pyranopterin monophosphate synthase
Synonym(s): MoaC
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 17.467
Isoelectric point: 7.132
Motif(s):
 
Type Positions Sequence Comment
2 -> 161 SQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD UniProt: Cyclic pyranopterin monophosphate synthase.
15 -> 150 MVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGG
17 -> 17 D UniProt: In Ref. 1; CAA49863..
21 -> 21 K UniProt: Loss of activity by 85%..
26 -> 26 R UniProt: Loss of activity by 80%..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.3 - cofactors, small molecule carriers --> 1.5.3.4 - molybdenum
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0032991 - protein-containing complex
molecular_function GO:0005515 - protein binding
GO:0016829 - lyase activity
GO:0042802 - identical protein binding
GO:0061799 - cyclic pyranopterin monophosphate synthase activity
biological_process GO:0006777 - Mo-molybdopterin cofactor biosynthetic process
External database links:  
ALPHAFOLD:
 P0A738
DIP:
 DIP-10230N
ECOCYC:
 EG11666-MONOMER
ECOLIWIKI:
 b0783
INTERPRO:
 IPR036522
INTERPRO:
 IPR023045
INTERPRO:
 IPR002820
PDB:
 4PYD
PDB:
 4PYA
PDB:
 1EKR
PDB:
 1EKS
PFAM:
 PF01967
PRIDE:
 P0A738
PRODB:
 PRO_000023262
REFSEQ:
 NP_415304
SMR:
 P0A738
UNIPROT:
 P0A738


Operon      
Name: moaABCDE         
Operon arrangement:
Transcription unit        Promoter
moaABCDE
moaABCDE
moaBCDE


Transcriptional Regulation      
Display Regulation             
Activated by: FNR, ModE
Repressed by: CueR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB