RegulonDB RegulonDB 11.1: Gene Form
   

umpG gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

nlpD truD umpG pcm ispF MqsA ArcA CRP ArcA CRP DksA-ppGpp DksA-ppGpp ppGpp surEp2 surEp2 nlpDp1 nlpDp1 nlpDp2 nlpDp2 TSS_3034 TSS_3034 rpoSp rpoSp rpoSp4 rpoSp4 rpoSp3 rpoSp3 TSS_3032 TSS_3032

Gene      
Name: umpG    Texpresso search in the literature
Synonym(s): ECK2739, EG11817, b2744, surE, ygbC
Genome position(nucleotides): 2869513 <-- 2870274
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.72
External database links:  
ASAP:
 ABE-0009008
CGSC:
 33215
ECHOBASE:
 EB1764
ECOLIHUB:
 surE
OU-MICROARRAY:
 b2744
STRING:
 511145.b2744
COLOMBOS: umpG


Product      
Name: broad specificity 5'(3')-nucleotidase and polyphosphatase
Synonym(s): SurE, UmpG, YgbC
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 26.9
Isoelectric point: 5.537
Motif(s):
 
Type Positions Sequence Comment
3 -> 180 ILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRH

 
Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0106411 - XMP 5'-nucleosidase activity
GO:0016787 - hydrolase activity
GO:0046872 - metal ion binding
GO:0008252 - nucleotidase activity
GO:0008253 - 5'-nucleotidase activity
GO:0000166 - nucleotide binding
GO:0004309 - exopolyphosphatase activity
GO:0008254 - 3'-nucleotidase activity
GO:0030145 - manganese ion binding
biological_process GO:0016311 - dephosphorylation
GO:0046050 - UMP catabolic process
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P0A840
DIP:
 DIP-47982N
ECOCYC:
 EG11817-MONOMER
ECOLIWIKI:
 b2744
INTERPRO:
 IPR030048
INTERPRO:
 IPR036523
INTERPRO:
 IPR002828
MODBASE:
 P0A840
PANTHER:
 PTHR30457
PFAM:
 PF01975
PRIDE:
 P0A840
PRODB:
 PRO_000024016
REFSEQ:
 NP_417224
SMR:
 P0A840
SWISSMODEL:
 P0A840
UNIPROT:
 P0A840


Operon      
Name: umpG-pcm         
Operon arrangement:
Transcription unit        Promoter
umpG-pcm


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3032 2867645 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3034 2868128 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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