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RegulonDB RegulonDB 11.1: Gene Form

rhaD gene in Escherichia coli K-12 genome

Gene local context to scale (view description)

Gene
Name:	rhaD
Synonym(s):	ECK3895, EG11866, b3902
Genome position(nucleotides):	4093448 <-- 4094272
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	55.76
External database links:

ASAP:	ABE-0012731
CGSC:	289
ECHOBASE:	EB1812
ECOLIHUB:	rhaD
OU-MICROARRAY:	b3902
STRING:	511145.b3902
COLOMBOS:	rhaD

Product

Name:

rhamnulose-1-phosphate aldolase

Synonym(s):

RhaD

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

30.145

Isoelectric point:

5.779

Motif(s):

Type	Positions	Sequence	Comment
	12 -> 238	GMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAQVL
	28 -> 28	R	UniProt: Severe loss of enzymatic activity..
	29 -> 29	N	UniProt: Severe loss of enzymatic activity..
	117 -> 117	E	UniProt: Loss of enzymatic activity..
	171 -> 171	E	UniProt: Loss of enzymatic activity..

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0005829 - cytosol
	molecular_function	GO:0016829 - lyase activity GO:0046872 - metal ion binding GO:0016832 - aldehyde-lyase activity GO:0008270 - zinc ion binding GO:0008994 - rhamnulose-1-phosphate aldolase activity GO:0042802 - identical protein binding
	biological_process	GO:0019299 - rhamnose metabolic process GO:0019301 - rhamnose catabolic process GO:0019323 - pentose catabolic process

Note(s):

Note(s): ...[more].

Reference(s):

[1] Calveras J., et al., 2009
[2] Jimenez A., et al., 2009

External database links:

ALPHAFOLD:

ECOCYC:

RHAMNULPALDOL-MONOMER

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

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PDB:

PDB:

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PFAM:

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PRODB:

REFSEQ:

SMART:

SMR:

UNIPROT:

Operon

Name:

rhaBAD

Operon arrangement:

Transcription unit	Promoter
rhaD	rhaDp
rhaBAD	rhaBp

Transcriptional Regulation
	Display Regulation
Activated by:	CRP, RhaS

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References

Reference(s)
[1] Calveras J., Egido-Gabas M., Gomez L., Casas J., Parella T., Joglar J., Bujons J., Clapes P., 2009, Dihydroxyacetone phosphate aldolase catalyzed synthesis of structurally diverse polyhydroxylated pyrrolidine derivatives and evaluation of their glycosidase inhibitory properties., Chemistry 15(30):7310-28
[2] Jimenez A., Clapes P., Crehuet R., 2009, Protein flexibility and metal coordination changes in DHAP-dependent aldolases., Chemistry 15(6):1422-8

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