RegulonDB RegulonDB 11.1: Gene Form
   

flgK gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

flgK flgL flgJ TSS_1351 TSS_1351 TSS_1350 TSS_1350 TSS_1349 TSS_1349 TSS_1348 TSS_1348 flgKp flgKp TSS_1347 TSS_1347

Gene      
Name: flgK    Texpresso search in the literature
Synonym(s): ECK1067, EG11967, b1082, flaS
Genome position(nucleotides): 1138378 --> 1140021
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.82
External database links:  
ASAP:
 ABE-0003660
CGSC:
 758
ECHOBASE:
 EB1910
ECOLIHUB:
 flgK
OU-MICROARRAY:
 b1082
STRING:
 511145.b1082
COLOMBOS: flgK


Product      
Name: flagellar hook-filament junction protein 1
Synonym(s): FlaS, FlgK
Sequence: Get amino acid sequence Fasta Format
Cellular location: extracellular space,cell projection
Molecular weight: 57.93
Isoelectric point: 4.253
Motif(s):
 
Type Positions Sequence Comment
2 -> 547 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR UniProt: Flagellar hook-associated protein 1.
5 -> 35 INNAMSGLNAAQAALNTASNNISSYNVAGYT
491 -> 546 ATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.12 - flagellum
  2 - information transfer --> 2.3 - protein related --> 2.3.4 - chaperoning, repair (refolding)
  5 - cell processes --> 5.3 - motility, chemotaxis, energytaxis (aerotaxis, redoxtaxis etc)
  6 - cell structure --> 6.4 - flagella
Gene Ontology Terms (GO)  
cellular_component GO:0005576 - extracellular region
GO:0009288 - bacterial-type flagellum
GO:0009424 - bacterial-type flagellum hook
molecular_function GO:0005198 - structural molecule activity
GO:0005515 - protein binding
biological_process GO:0044780 - bacterial-type flagellum assembly
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P33235
DIP:
 DIP-9639N
ECOCYC:
 EG11967-MONOMER
ECOLIWIKI:
 b1082
INTERPRO:
 IPR002371
INTERPRO:
 IPR010930
INTERPRO:
 IPR001444
PANTHER:
 PTHR30033
PFAM:
 PF00460
PFAM:
 PF06429
PRIDE:
 P33235
PRINTS:
 PR01005
PRODB:
 PRO_000022646
REFSEQ:
 NP_415600
SMR:
 P33235
UNIPROT:
 P33235


Operon      
Name: flgKLO         
Operon arrangement:
Transcription unit        Promoter
flgK


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1347 1137587 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1348 1138353 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1349 1140510 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1350 1140515 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1351 1140518 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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