RegulonDB RegulonDB 11.1: Gene Form
   

nuoJ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

nuoL nuoJ nuoI nuoK TSS_2542 TSS_2542 TSS_2541 TSS_2541 TSS_2540 TSS_2540 TSS_2539 TSS_2539 TSS_2538 TSS_2538 TSS_2537 TSS_2537 TSS_2536 TSS_2536 TSS_2535 TSS_2535 TSS_2534 TSS_2534

Gene      
Name: nuoJ    Texpresso search in the literature
Synonym(s): ECK2274, EG12090, b2280
Genome position(nucleotides): 2395342 <-- 2395896
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.87
External database links:  
ASAP:
 ABE-0007536
CGSC:
 32652
ECHOBASE:
 EB2014
ECOLIHUB:
 nuoJ
OU-MICROARRAY:
 b2280
STRING:
 511145.b2280
COLOMBOS: nuoJ


Product      
Name: NADH:quinone oxidoreductase subunit J
Synonym(s): NADH:ubiquinone oxidoreductase, membrane subunit J, NuoJ
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 19.875
Isoelectric point: 5.588
Motif(s):
 
Type Positions Sequence Comment
1 -> 21 MEFAFYICGLIAILATLRVIT UniProt: Helical.
17 -> 157 LRVITHTNPVHALLYLIISLLAISGVFFSLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAIMLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFH
28 -> 48 ALLYLIISLLAISGVFFSLGA UniProt: Helical.
54 -> 74 LEIIVYAGAIMVLFVFVVMML UniProt: Helical.
85 -> 85 R UniProt: In Ref. 1; CAA48369..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.6 - aerobic respiration
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.7 - anaerobic respiration
  1 - metabolism --> 1.4 - energy production/transport --> 1.4.1 - electron donors
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.D - Oxidoreduction-driven Active Transporters
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0030964 - NADH dehydrogenase complex
GO:0045271 - respiratory chain complex I
GO:0045272 - plasma membrane respiratory chain complex I
molecular_function GO:0003954 - NADH dehydrogenase activity
GO:0008137 - NADH dehydrogenase (ubiquinone) activity
GO:0048038 - quinone binding
biological_process GO:0022904 - respiratory electron transport chain
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P0AFE0
DIP:
 DIP-59258N
ECOCYC:
 NUOJ-MONOMER
ECOLIWIKI:
 b2280
INTERPRO:
 IPR001457
INTERPRO:
 IPR042106
PFAM:
 PF00499
PRIDE:
 P0AFE0
PRODB:
 PRO_000023437
REFSEQ:
 NP_416783
SMR:
 P0AFE0
UNIPROT:
 P0AFE0


Operon      
Name: nuoABCEFGHIJKLMN         
Operon arrangement:
Transcription unit        Promoter
nuoABCEFGHIJKLMN
nuoABCEFGHIJKLMN
nuoMN


Transcriptional Regulation      
Display Regulation             
Activated by: NarL, Fis
Repressed by: FNR, IHF, ArcA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2534 2393605 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2535 2393635 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2536 2393749 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2537 2394474 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2538 2394595 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2539 2394680 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2540 2396044 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2541 2396059 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2542 2396436 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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