RegulonDB RegulonDB 11.1: Gene Form
   

treB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

treC treB treR ArcA TreR CRP TreR CRP anti-terminator terminator treBp treBp

Gene      
Name: treB    Texpresso search in the literature
Synonym(s): ECK4235, EG12127, b4240
Genome position(nucleotides): 4464759 <-- 4466180
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.36
External database links:  
ASAP:
 ABE-0013872
CGSC:
 34601
ECHOBASE:
 EB2048
ECOLIHUB:
 treB
OU-MICROARRAY:
 b4240
STRING:
 511145.b4240
COLOMBOS: treB


Shine dalgarno      
Sequence: gtcatctgccATGGGGcttTAT


Product      
Name: trehalose-specific PTS enzyme IIBC component
Synonym(s): Enzyme IIBCtre, TreB, enzyme IIBC component of trehalose PTS
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 51.081
Isoelectric point: 9.224
Motif(s):
 
Type Positions Sequence Comment
1 -> 89 MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANARPKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVD UniProt: PTS EIIB type-1.
13 -> 40 LIELVGGRGNIATVSHCITRLRFVLNQP
109 -> 473 SHFAVIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFLWLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDFGMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHALIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQSMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGINLKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAIIIPIVLTSFIYQRKYRLGTLDIV UniProt: PTS EIIC type-1.
111 -> 131 FAVIFFPLLPALISGGLILGF UniProt: Helical.
114 -> 405 IFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFLWLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDFGMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHALIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQSMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGINLKYRFPMLCAMIG

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.9 - misc. glucose metabolism
  4 - transport --> 4.4 - Group Translocators --> 4.4.A - Phosphotransferase Systems (PEP-dependent PTS)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005515 - protein binding
GO:0016740 - transferase activity
GO:0016301 - kinase activity
GO:0008982 - protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO:0015574 - trehalose transmembrane transporter activity
GO:0090563 - protein-phosphocysteine-sugar phosphotransferase activity
GO:0090589 - protein-phosphocysteine-trehalose phosphotransferase system transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0016310 - phosphorylation
GO:0015771 - trehalose transport
GO:0034219 - carbohydrate transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P36672
ECOCYC:
 TREB-MONOMER
ECOLIWIKI:
 b4240
INTERPRO:
 IPR036878
INTERPRO:
 IPR018113
INTERPRO:
 IPR013013
INTERPRO:
 IPR011296
INTERPRO:
 IPR004719
INTERPRO:
 IPR003352
INTERPRO:
 IPR001996
MINT:
 P36672
MODBASE:
 P36672
PFAM:
 PF00367
PFAM:
 PF02378
PRIDE:
 P36672
PRODB:
 PRO_000024107
PROSITE:
 PS51103
PROSITE:
 PS01035
PROSITE:
 PS51098
REFSEQ:
 NP_418661
SMR:
 P36672
UNIPROT:
 P36672


Operon      
Name: treBC         
Operon arrangement:
Transcription unit        Promoter
treBC


Transcriptional Regulation      
Display Regulation             
Activated by: ArcA
Repressed by: CRP, TreR
Undetermined regulation CRP


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB