RegulonDB RegulonDB 11.1: Gene Form
   

yadM gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

htrE yadL yadM

Gene      
Name: yadM    Texpresso search in the literature
Synonym(s): ECK0137, EG12327, b0138
Genome position(nucleotides): 152243 <-- 152812
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 42.81
External database links:  
ASAP:
 ABE-0000477
ECHOBASE:
 EB2231
ECOLIHUB:
 yadM
OU-MICROARRAY:
 b0138
STRING:
 511145.b0138
COLOMBOS: yadM


Product      
Name: putative fimbrial protein YadM
Synonym(s): YadM
Sequence: Get amino acid sequence Fasta Format
Cellular location: extracellular space,pilus
Molecular weight: 20.307
Isoelectric point: 8.2
Motif(s):
 
Type Positions Sequence Comment
1 -> 23 MIKTTPHKIVILMGILLSPSVFA
24 -> 189 TDINVEFTATVKATTCNITLTGNNVTNDGNNNYTLRIPKMGLDKIANKTTESQADFKLVASGCSSGISWIDTTLTGNASSSSPKLIIPQSGDSSSTTSNIGMGFKKRTTDDATFLKPNSAEKIRWSTDEMQPDKGLEMTVALRETDAGQGVPGNFRALATFNFIYQ UniProt: Uncharacterized fimbrial-like protein YadM.
29 -> 189 EFTATVKATTCNITLTGNNVTNDGNNNYTLRIPKMGLDKIANKTTESQADFKLVASGCSSGISWIDTTLTGNASSSSPKLIIPQSGDSSSTTSNIGMGFKKRTTDDATFLKPNSAEKIRWSTDEMQPDKGLEMTVALRETDAGQGVPGNFRALATFNFIYQ
104 -> 125 SSPKLIIPQSGDSSSTTSNIGM UniProt: Disordered; Sequence Annotation Type: region of interest.

 
Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.5 - pilus
Gene Ontology Terms (GO)  
cellular_component GO:0009289 - pilus
GO:0005576 - extracellular region
biological_process GO:0007155 - cell adhesion
GO:0043709 - cell adhesion involved in single-species biofilm formation
Note(s): Note(s): ...[more].
Evidence: [COMP-HINF-FN-FROM-SEQ] Human inference of function from sequence
[EXP-IMP] Inferred from mutant phenotype
Reference(s): [1] Korea CG., et al., 2010
[2] Korea CG., et al., 2011
[3] Larsonneur F., et al., 2016
[4] Wurpel DJ., et al., 2013
External database links:  
ALPHAFOLD:
 P37018
ECOCYC:
 EG12327-MONOMER
ECOLIWIKI:
 b0138
INTERPRO:
 IPR008966
INTERPRO:
 IPR036937
INTERPRO:
 IPR000259
PFAM:
 PF00419
PRIDE:
 P37018
REFSEQ:
 NP_414680
UNIPROT:
 P37018


Operon      
Name: yadMLKC         
Operon arrangement:
Transcription unit        Promoter
yadC
yadMLKC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Korea CG., Badouraly R., Prevost MC., Ghigo JM., Beloin C., 2010, Escherichia coli K-12 possesses multiple cryptic but functional chaperone-usher fimbriae with distinct surface specificities., Environ Microbiol 12(7):1957-77

 [2] Korea CG., Ghigo JM., Beloin C., 2011, The sweet connection: Solving the riddle of multiple sugar-binding fimbrial adhesins in Escherichia coli: Multiple E. coli fimbriae form a versatile arsenal of sugar-binding lectins potentially involved in surface-colonisation and tissue tropism., Bioessays 33(4):300-11

 [3] Larsonneur F., Martin FA., Mallet A., Martinez-Gil M., Semetey V., Ghigo JM., Beloin C., 2016, Functional analysis of Escherichia coli Yad fimbriae reveals their potential role in environmental persistence., Environ Microbiol 18(12):5228-5248

 [4] Wurpel DJ., Beatson SA., Totsika M., Petty NK., Schembri MA., 2013, Chaperone-usher fimbriae of Escherichia coli., PLoS One 8(1):e52835

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