RegulonDB RegulonDB 11.1: Gene Form
   

fadK gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ppsA fadK ydiT ydiS

Gene      
Name: fadK    Texpresso search in the literature
Synonym(s): ECK1699, EG12357, b1701, ydiD
Genome position(nucleotides): 1782977 --> 1784677
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 49.85
External database links:  
ASAP:
 ABE-0005676
ECHOBASE:
 EB2260
ECOLIHUB:
 fadK
OU-MICROARRAY:
 b1701
STRING:
 511145.b1701
COLOMBOS: fadK


Product      
Name: short chain acyl-CoA synthetase
Synonym(s): FadK, YdiD
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,cytosol
Molecular weight: 62.759
Isoelectric point: 6.561
Motif(s):
 
Type Positions Sequence Comment
49 -> 457 QQTARAMPDKIAVVDNHGASYTYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKIGAVSVPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKLAPATSSLSLSQIIADNTSLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILASERAYCARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQRCTCMLGATPFVYDLLNVLEKQPADLSALRFFLCGGTTIPKKVARECQQRGIKLLSVYGSTESSPHAVVNLDDPLSRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNVFMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVR
231 -> 242 ILASERAYCARL UniProt: ATP.
466 -> 543 EVEDILLQHPKIHDACVVAMSDERLGERSCAYVVLKAPHHSLSLEEVVAFFSRKRVAKYKYPEHIVVIEKLPRTTSGK

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.2 - fatty acids
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0016020 - membrane
GO:0005886 - plasma membrane
molecular_function GO:0016874 - ligase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0031956 - medium-chain fatty acid-CoA ligase activity
biological_process GO:0006629 - lipid metabolic process
GO:0006631 - fatty acid metabolic process
GO:0019395 - fatty acid oxidation
GO:0006635 - fatty acid beta-oxidation
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P38135
ECOCYC:
 EG12357-MONOMER
ECOLIWIKI:
 b1701
INTERPRO:
 IPR000873
INTERPRO:
 IPR020845
INTERPRO:
 IPR025110
INTERPRO:
 IPR042099
MODBASE:
 P38135
PFAM:
 PF00501
PFAM:
 PF13193
PRIDE:
 P38135
PRODB:
 PRO_000022571
PROSITE:
 PS00455
REFSEQ:
 NP_416216
SMR:
 P38135
UNIPROT:
 P38135


Operon      
Name: ydiQRST-fadK         
Operon arrangement:
Transcription unit        Promoter
ydiQRST-fadK


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB