RegulonDB RegulonDB 11.0: Gene Form
   

lgoT gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

tsr lgoT lgoR UxuR ExuR yjjLp8 yjjLp8 yjjLp6 yjjLp6 yjjLp7 yjjLp7 yjjLp5 yjjLp5

Gene      
Name: lgoT    Texpresso search in the literature
Synonym(s): ECK4346, EG12587, b4356, yjiZ, yjjL
Genome position(nucleotides): 4593361 <-- 4594722
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.98
External database links:  
ASAP:
ABE-0014284
ECHOBASE:
EB2473
ECOLIHUB:
yjjL
OU-MICROARRAY:
b4356
STRING:
511145.b4356
COLOMBOS: lgoT


Product      
Name: galactonate:H+ symporter
Synonym(s): L-galactonate MFS transporter, LgoT, YjiZ, YjjL
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 49.44
Isoelectric point: 9.385
Motif(s):
 
Type Positions Sequence Comment
1 -> 23 MEKENITIDPRSSFTPSSSADIP UniProt: Disordered; Sequence Annotation Type: region of interest.
43 -> 63 AMLLLFFAAVINYLDRSSLSV UniProt: Helical.
47 -> 408 LFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAP
72 -> 92 LGLSATEIGALLSVFSLAYGI UniProt: Helical.
108 -> 128 LMLGLGMFFWSLFQAMSGMVH UniProt: Helical.

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0042873 - aldonate transmembrane transport
GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
P39398
DIP:
DIP-12656N
ECOCYC:
YJIZ-MONOMER
ECOLIWIKI:
b4356
INTERPRO:
IPR011701
INTERPRO:
IPR000849
INTERPRO:
IPR036259
INTERPRO:
IPR020846
MODBASE:
P39398
PFAM:
PF07690
PRIDE:
P39398
PROSITE:
PS50850
REFSEQ:
NP_418776
UNIPROT:
P39398


Operon      
Name: lgoT         
Operon arrangement:
Transcription unit        Promoter
lgoT


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yjjLp5 4594737 reverse nd [ICWHO] [1]
  promoter yjjLp7 4594837 reverse nd [ICWHO] [1]
  promoter yjjLp6 4594844 reverse nd [ICWHO] [1]
  promoter yjjLp8 4594882 reverse nd [ICWHO] [1]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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