RegulonDB RegulonDB 11.1: Gene Form
   

yafY gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yafZ ykfB yafY ykfL ykfK anti-anti-terminator anti-terminator terminator anti-terminator ykfBp2 ykfBp2 ykfBp1 ykfBp1

Gene      
Name: yafY    Texpresso search in the literature
Synonym(s): ECK0253, G6126, b0251
Genome position(nucleotides): 266110 <-- 266553
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 50.68
External database links:  
ASAP:
 ABE-0000853
ECHOBASE:
 EB3121
ECOLIHUB:
 yafY
OU-MICROARRAY:
 b0251
STRING:
 511145.b0251
COLOMBOS: yafY


Product      
Name: CP4-6 prophage; inner membrane lipoprotein YafY
Synonym(s): YafY
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 16.815
Isoelectric point: 4.317
Motif(s):
 
Type Positions Sequence Comment
1 -> 20 MKRKTLPLLALVATTLFLIA
21 -> 147 CDDRSDDLKAISKFKDLTPPRFSDVVSHQDDVSEEWSQVDYLSGPTLQVLRTRQSPDGCEDGSYYYLVDMQEKTVQPLMNALCIADNIKLEYQEVTDPYTKEKYFEYAHDGKLMGQLLIPSNPDNQE UniProt: Lipoprotein YafY.
22 -> 23 DD UniProt: Still induces degP when overexpressed, remains in inner membrane..
35 -> 146 KDLTPPRFSDVVSHQDDVSEEWSQVDYLSGPTLQVLRTRQSPDGCEDGSYYYLVDMQEKTVQPLMNALCIADNIKLEYQEVTDPYTKEKYFEYAHDGKLMGQLLIPSNPDNQ
60 -> 60 D UniProt: 5-fold decrease in degP induction when overexpressed..

 
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
Note(s): Note(s): ...[more].
Reference(s): [1] Rao S., et al., 2020
External database links:  
ALPHAFOLD:
 P77365
ECOCYC:
 G6126-MONOMER
ECOLIWIKI:
 b0251
PFAM:
 PF20494
PRIDE:
 P77365
PROSITE:
 PS51257
REFSEQ:
 NP_414785
SMR:
 P77365
UNIPROT:
 P77365


Operon      
Name: yafY-ykfBF-yafX-ykfGH-yafW-ykfI         
Operon arrangement:
Transcription unit        Promoter
ykfBF-yafX-ykfGH-yafW-ykfI
ykfBF-yafX-ykfGH-yafW-ykfI
ykfGH-yafW-ykfI
yafY-ykfBF-yafX-ykfGH-yafW-ykfI


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Rao S., Bates GT., Matthews CR., Newport TD., Vickery ON., Stansfeld PJ., 2020, Characterizing Membrane Association and Periplasmic Transfer of Bacterial Lipoproteins through Molecular Dynamics Simulations., Structure 28(4):475-487.e3

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