RegulonDB

Gene
Name:	rclB
Synonym(s):	ECK0302, G6173, b0303, ykgI
Genome position(nucleotides):	318331 <-- 318567 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	35.44
External database links:

ASAP:	ABE-0001043
ECHOBASE:	EB4026
OU-MICROARRAY:	b0303
PortEco:	ykgI
STRING:	511145.b0303
COLOMBOS:	rclB

Product

Name:

DUF1471 domain-containing protein RclB

Synonym(s):

RclB, YkgI, putative protein, hypochlorite stress response

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol,periplasmic space

Molecular weight:

8.472

Isoelectric point:

10.058

Motif(s):

Type	Positions	Sequence
	30 -> 78	HISVSSVSASPTVLEDTIADIARKYNASSWKVTSMRIDNNSTATAVLYK
	1 -> 22	MFKKSVLFATLLSGVMAFSTNA
	23 -> 78	DDKIILKHISVSSVSASPTVLEDTIADIARKYNASSWKVTSMRIDNNSTATAVLYK

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		5 - cell processes --> 5.6 - protection
Gene Ontology Terms (GO)
	cellular_component	GO:0005829 - cytosol GO:0042597 - periplasmic space
	biological_process	GO:1901530 - response to hypochlorite

Note(s):

Note(s): ...[more].

Evidence:

[IMP] Inferred from mutant phenotype

Reference(s):

[1] Parker BW., et al., 2013

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

PFAM:

PRIDE:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

rclABC

Operon arrangement:

Transcription unit	Promoter
rclABC	ykgCp1

Transcriptional Regulation
	Display Regulation
Activated by:	RclR

Regulation by small RNA
	Display Regulation
small RNA	omrB

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	ykgBp10	318334	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.933. P-value: 1.201e-5 Read more >	[ICWHO]	[2]
promoter	ykgBp3	318376	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 2.896. P-value: 5.657e-5 Read more >	[ICWHO]	[2]
promoter	ykgBp4	318397	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: 3.064. P-value: 4.149e-5 Read more >	[ICWHO]	[2]
promoter	ykgBp7	318484	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 3.404. P-value: 6.378e-5 Read more >	[ICWHO]	[2]
promoter	ykgBp9	318525	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.683. P-value: 2.040e-5 Read more >	[ICWHO]	[2]

Evidence
[ICWHO] Inferred computationally without human oversight

Reference(s)
[1] Parker BW., Schwessinger EA., Jakob U., Gray MJ., 2013, The RclR protein is a reactive chlorine-specific transcription factor in Escherichia coli., J Biol Chem 288(45):32574-84
[2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78