RegulonDB

Gene
Name:	gfcA
Synonym(s):	ECK0978, G6508, b0987, ymcD
Genome position(nucleotides):	1049439 <-- 1049744 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	57.52
External database links:

ASAP:	ABE-0003325
ECHOBASE:	EB3496
OU-MICROARRAY:	b0987
PortEco:	gfcA
STRING:	511145.b0987
COLOMBOS:	gfcA

Product

Name:

threonine-rich inner membrane protein GfcA

Synonym(s):

GfcA, YmcD

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

9.507

Isoelectric point:

6.504

Motif(s):

Type	Positions	Sequence
	60 -> 80	VGTATVVGVATAVGVATLAVV
	1 -> 21	MKHKLSAILMAFMLTTPAAFA
	22 -> 101	APEATNGTEATTGTTGTTTTTTGATTTATTTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTTR
	15 -> 100	TTPAAFAAPEATNGTEATTGTTGTTTTTTGATTTATTTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTT

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
Gene Ontology Terms (GO)	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane

Note(s):

Note(s): ...[more].

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

PRIDE:

PRODB:

REFSEQ:

UNIPROT:

Operon

Name:

gfcA

Operon arrangement:

Transcription unit	Promoter
gfcA	gfcAp

Transcriptional Regulation
	Display Regulation
Repressed by:	YjjQ

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	gfcAp1	1049834		reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: -3.53. P-value: 9.516e-5 Read more >	[ICWHO]	[1]
	promoter	TSS_1308	1049998		reverse	nd	[RS-EPT-CBR]	[2]

Evidence
[ICWHO] Inferred computationally without human oversight
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)