RegulonDB RegulonDB 11.1: Gene Form
   

mokB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

trg mokB hokB yncP sokB CRP Fis Fis terminator trgp trgp mokBp3 mokBp3 sokBp sokBp sokBp3 sokBp3 TSS_1805 TSS_1805

Gene      
Name: mokB    Texpresso search in the literature
Synonym(s): ECK1413, G6736, b1420
Genome position(nucleotides): 1491962 <-- 1492129
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.19
External database links:  
ASAP:
 ABE-0004738
ECHOBASE:
 EB4159
ECOLIHUB:
 mokB
OU-MICROARRAY:
 b1420
STRING:
 511145.b1420
COLOMBOS: mokB


Product      
Name: putative regulatory protein MokB
Synonym(s): MokB, regulatory peptide whose translation enables hokB expression
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 5.894
Isoelectric point: 6.795
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
Note(s): Note(s): ...[more].
Reference(s): [1] Schneider D., et al., 2000
[2] Woods R., et al., 2006
External database links:  
ALPHAFOLD:
 P76096
ECOCYC:
 G6736-MONOMER
ECOLIWIKI:
 b1420
PRIDE:
 P76096
REFSEQ:
 NP_415937
SMR:
 P76096
UNIPROT:
 P76096


Operon      
Name: mokB         
Operon arrangement:
Transcription unit        Promoter
mokB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1805 1491888 forward nd [RS-EPT-CBR] [3]
  promoter sokBp3 1492116 forward nd [COMP-AINF] [4]
  promoter mokBp3 1492305 reverse nd [COMP-AINF] [4]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Schneider D., Duperchy E., Coursange E., Lenski RE., Blot M., 2000, Long-term experimental evolution in Escherichia coli. IX. Characterization of insertion sequence-mediated mutations and rearrangements., Genetics 156(2):477-88

 [2] Woods R., Schneider D., Winkworth CL., Riley MA., Lenski RE., 2006, Tests of parallel molecular evolution in a long-term experiment with Escherichia coli., Proc Natl Acad Sci U S A 103(24):9107-12

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [4] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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