RegulonDB RegulonDB 11.1: Gene Form
   

ydcU gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

patD ydcT ydcU ydcV patDp4 patDp4 patDp3 patDp3

Gene      
Name: ydcU    Texpresso search in the literature
Synonym(s): ECK1436, G6753, b1442
Genome position(nucleotides): 1513831 --> 1514772
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.97
External database links:  
ASAP:
 ABE-0004807
ECHOBASE:
 EB3527
ECOLIHUB:
 ydcU
OU-MICROARRAY:
 b1442
STRING:
 511145.b1442
COLOMBOS: ydcU


Product      
Name: putative ABC transporter membrane subunit YdcU
Synonym(s): YdcU
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 34.36
Isoelectric point: 9.823
Motif(s):
 
Type Positions Sequence Comment
26 -> 46 GLGLFLLLLGPLMWFGIVYFG UniProt: Helical.
87 -> 302 ILRTLTMAVAVTIASAILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHLGLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQASADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQQGAIGNMPMAAAFTLVPIILIALYLA UniProt: ABC transmembrane type-1.
93 -> 113 MAVAVTIASAILAFPMAWYMA UniProt: Helical.
106 -> 307 FPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHLGLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQASADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQQGAIGNMPMAAAFTLVPIILIALYLAFVKRL
123 -> 143 FFYIAVMLPMWASYIVKAYAW UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.1 - membrane
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.m - ABC superfamily, membrane component
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
biological_process GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ALPHAFOLD:
 P77156
ECOCYC:
 YDCU-MONOMER
ECOLIWIKI:
 b1442
INTERPRO:
 IPR035906
INTERPRO:
 IPR000515
PFAM:
 PF00528
PRIDE:
 P77156
PROSITE:
 PS50928
REFSEQ:
 NP_415959
UNIPROT:
 P77156


Operon      
Name: ydcSTUV-patD         
Operon arrangement:
Transcription unit        Promoter
ydcSTUV-patD
patD


Transcriptional Regulation      
Display Regulation             
Activated by: Nac


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter patDp3 1515415 forward nd [COMP-AINF] [2]
  promoter patDp4 1515440 forward nd [COMP-AINF] [2]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

RegulonDB