RegulonDB RegulonDB 11.0: Gene Form
   

ydeP gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ydeP ydeQ safA EvgA NagC PhoP EvgA PhoP PhoP ydePp ydePp safAp safAp

Gene      
Name: ydeP    Texpresso search in the literature
Synonym(s): ECK1494, G6791, b1501
Genome position(nucleotides): 1584207 <-- 1586486
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 50.31
External database links:  
ASAP:
 ABE-0005001
ECHOBASE:
 EB3559
ECOLIHUB:
 ydeP
OU-MICROARRAY:
 b1501
STRING:
 511145.b1501
COLOMBOS: ydeP


Product      
Name: putative oxidoreductase YdeP
Synonym(s): YdeP, acid resistance protein
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,periplasmic space
Molecular weight: 83.495
Isoelectric point: 6.751
Motif(s):
 
Type Positions Sequence Comment
108 -> 423 RLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAAFLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHNPGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYYNVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEWKDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNIGKPGAGICPLRGHSNVQGDRTVGITEKPSAE
642 -> 751 LVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAKICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHDPLSGIPGYKSI

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism
  5 - cell processes --> 5.5 - adaptations --> 5.5.4 - pH
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0030288 - outer membrane-bounded periplasmic space
molecular_function GO:0046872 - metal ion binding
GO:0016491 - oxidoreductase activity
GO:0051536 - iron-sulfur cluster binding
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0008863 - formate dehydrogenase (NAD+) activity
GO:0030151 - molybdenum ion binding
GO:0043546 - molybdopterin cofactor binding
biological_process GO:0010447 - response to acidic pH
Note(s): Note(s): ...[more].
Evidence: [IGI] Inferred from genetic interaction
[IMP] Inferred from mutant phenotype
Reference(s): [1] Masuda N., et al., 2002
[2] Masuda N., et al., 2003
External database links:  
ALPHAFOLD:
 P77561
DIP:
 DIP-28057N
ECOCYC:
 G6791-MONOMER
ECOLIWIKI:
 b1501
INTERPRO:
 IPR041953
INTERPRO:
 IPR010046
INTERPRO:
 IPR009010
INTERPRO:
 IPR006656
INTERPRO:
 IPR037951
MODBASE:
 P77561
PANTHER:
 PTHR43105:SF4
PFAM:
 PF00384
PFAM:
 PF01568
PRIDE:
 P77561
REFSEQ:
 NP_416018
UNIPROT:
 P77561


Operon      
Name: ydeP         
Operon arrangement:
Transcription unit        Promoter
ydeP


Transcriptional Regulation      
Display Regulation             
Activated by: EvgA, UvrY, NarL, RcsB
Repressed by: H-NS, PhoP, NagC, NarP


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Masuda N., Church GM., 2002, Escherichia coli gene expression responsive to levels of the response regulator EvgA., J Bacteriol 184(22):6225-34

 [2] Masuda N., Church GM., 2003, Regulatory network of acid resistance genes in Escherichia coli., Mol Microbiol 48(3):699-712

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