RegulonDB RegulonDB 10.7: Gene Form
   

hyfC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

hyfB hyfD hyfC

Gene      
Name: hyfC    Texpresso search in the literature
Synonym(s): ECK2479, G7300, b2483
Genome position(nucleotides): 2603847 --> 2604794 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.69
Reference(s): [1] Andrews SC., et al., 1997
External database links:  
ASAP:
ABE-0008183
ECHOBASE:
EB3963
OU-MICROARRAY:
b2483
PORTECO:
hyfC
REGULONDB:
b2483
STRING:
511145.b2483
M3D: hyfC
COLOMBOS: hyfC
PortEco: b2483


Product      
Name: hydrogenase 4 component C
Synonym(s): HyfC
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 34.359
Isoelectric point: 8.331
Motif(s):
 
Type Positions Sequence
229 -> 249 WGLGLKQVVMASLFVALFLPF
99 -> 119 FAGGGDLITLIYLLALFRFFF
11 -> 31 VIFALAQAVILLMLTPLFTGI
257 -> 277 LACLLTSLVVTLLKVLLIFVL
18 -> 311 AVILLMLTPLFTGISRQIRARMHSRRGPGIWQDYRDIHKLFKRQEVAPTSSGLMFRLMPWVLISSMLVLAMALPLFITVSPFAGGGDLITLIYLLALFRFFFALSGLDTGSPFAGVGASRELTLGILVEPMLILSLLVLALIAGSTHIEMISNTLAMGWNSPLTTVLALLACGFACFIEMGKIPFDVAEAEQELQEGPLTEYSGAGLALAKWGLGLKQVVMASLFVALFLPFGRAQELSLACLLTSLVVTLLKVLLIFVLASIAENTLARGRFLLIHHVTWLGFSLAALAWVFW

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.7 - anaerobic respiration
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0044569 - [Ni-Fe] hydrogenase complex
molecular_function GO:0016491 - oxidoreductase activity
biological_process GO:0006974 - cellular response to DNA damage stimulus
GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
Reference(s): [1] Andrews SC., et al., 1997
External database links:  
ECOCYC:
MONOMER0-154
ECOLIWIKI:
b2483
INTERPRO:
IPR018086
INTERPRO:
IPR001694
PANTHER:
PTHR11432
PFAM:
PF00146
PRIDE:
P77858
PRODB:
PRO_000022965
PROSITE:
PS00668
PROTEINMODELPORTAL:
P77858
REFSEQ:
NP_416978
SMR:
P77858
UNIPROT:
P77858


Operon      
Name: hyfABCDEFGHIJR-focB         
Operon arrangement:
Transcription unit        Promoter
hyfABCDEFGHIJR-focB


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FhlA, HyfR
Repressed by: FNR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Andrews SC., Berks BC., McClay J., Ambler A., Quail MA., Golby P., Guest JR., 1997, A 12-cistron Escherichia coli operon (hyf) encoding a putative proton-translocating formate hydrogenlyase system., Microbiology 143 ( Pt 11):3633-47


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