RegulonDB

Gene
Name:	yhgE
Synonym(s):	ECK3389, G7745, b3402
Genome position(nucleotides):	3530715 <-- 3532439
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	50.09
Note(s):	ArcA appears to activate yhgE gene expression under anaerobiosis. A putative ArcA binding site is located 172 bp upstream of this gene Salmon KA,2005.
External database links:

ASAP:	ABE-0011098
ECHOBASE:	EB2767
ECOLIHUB:	yhgE
OU-MICROARRAY:	b3402
STRING:	511145.b3402
COLOMBOS:	yhgE

Product

Name:

putative transport protein YhgE

Synonym(s):

YhgE

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

64.637

Isoelectric point:

9.297

Motif(s):

Type	Positions	Sequence	Comment
	12 -> 32	WGMIATGLLQGLVCYLLIAWL	UniProt: Helical.
	39 -> 59	WIVYGVPATVAFSSVLLFSVI	UniProt: Helical.
	52 -> 415	SVLLFSVISFKQKRLWGWLALVFIATLGMSGWLKWQTDGMNPWRAEKALWDFGCYLLLMAMLLLPWIQQSLRIRNDSSRYRYFYQSVWHNVLILLVIFLANGLTWLVLLLWSELFKLVGITFFNTLFFATDWFIYLTLGLVTALAVILARTQSRLIDSIQKLFTLIATGLLPLVSLLTLMFIITLPFTGLSAISRHISAAGLLLTLAFLQLILMAIVRDPQKASLPWTGPLRCLIKTALLVAPLYVFVAAWALWLRVAQYGWTVDRLQGVLAVLVLLVWSLGYFVSIVWRKGQNPVVLQGKVNLAVSLLVLVILVLLNSPVLDSMRISVNSHMARYQSGKNTSDQVTIYMLEQSGRYGRAALES
	66 -> 86	LWGWLALVFIATLGMSGWLKW	UniProt: Helical.
	99 -> 119	ALWDFGCYLLLMAMLLLPWIQ	UniProt: Helical.

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		4 - transport --> 4.9.B - Putative uncharacterized transport protein
Gene Ontology Terms (GO)
Gene Ontology Terms (GO)	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0016021 - integral component of membrane

Note(s):

Note(s): ...[more].

External database links:

ALPHAFOLD:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PFAM:

PRIDE:

REFSEQ:

UNIPROT:

Operon

Name:

yhgE

Operon arrangement:

Transcription unit	Promoter
yhgE

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	yhgEp7	3532485	reverse	nd	[COMP-AINF]	[1]
promoter	yhgEp9	3532538	reverse	nd	[COMP-AINF]	[1]
promoter	yhgEp6	3532588	reverse	nd	[COMP-AINF]	[1]
promoter	TSS_3999 (cluster)	3532790	forward	nd	[RS-EPT-CBR]	[2]
promoter	TSS_4000	3532798	forward	nd	[RS-EPT-CBR]	[2]

Evidence
[COMP-AINF] Inferred computationally without human oversight
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.