RegulonDB RegulonDB 10.9: Gene Form
   

yjhH gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yjhG yjhH yjhI yjhGp4 yjhGp4 yjhGp3 yjhGp3

Gene      
Name: yjhH    Texpresso search in the literature
Synonym(s): ECK4287, G7911, b4298
Genome position(nucleotides): 4524105 <-- 4525010 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
52.65
External database links:  
ASAP:
ABE-0014089
ECHOBASE:
EB2438
ECOLIHUB:
yjhH
OU-MICROARRAY:
b4298
STRING:
511145.b4298
COLOMBOS: yjhH


Product      
Name: KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase
Synonym(s): YjhH
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 32.722
Isoelectric point: 5.13
Motif(s):
 
Type Positions Sequence
3 -> 295 KFSGIIPPVSSTFHRDGTLDKKAMREVADFLINKGVDGLFYLGTGGEFSQMNTAQRMALAEEAVTIVDGRVPVLIGVGSPSTDEAVKLAQHAQAYGADGIVAINPYYWKVAPRNLDDYYQQIARSVTLPVILYNFPDLTGQDLTPETVTRLALQNENIVGIKDTIDSVGHLRTMINTVKSVRPSFSVFCGYDDHLLNTMLLGGDGAITASANFAPELSVGIYRAWREGDLATAATLNKKLLQLPAIYALETPFVSLIKYSMQCVGLPVETYCLPPILEASEEAKDKVHVLLTA

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.1 - unassigned reversible reactions
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003824 - catalytic activity
GO:0016829 - lyase activity
GO:0047440 - 2-dehydro-3-deoxy-D-pentonate aldolase activity
biological_process GO:0046176 - aldonic acid catabolic process
Note(s): Note(s): ...[more].
Reference(s): [1] Cabulong RB., et al., 2018
[2] Gao H., et al., 2017
[3] Tai YS., et al., 2016
[4] Zhang N., et al., 2016
External database links:  
DIP:
DIP-12622N
ECOCYC:
G7911-MONOMER
ECOLIWIKI:
b4298
INTERPRO:
IPR002220
INTERPRO:
IPR020625
INTERPRO:
IPR020624
INTERPRO:
IPR013785
MODBASE:
P39359
PANTHER:
PTHR12128
PFAM:
PF00701
PRIDE:
P39359
PRINTS:
PR00146
PROSITE:
PS00665
PROSITE:
PS00666
REFSEQ:
NP_418718
SMART:
SM01130
SMR:
P39359
UNIPROT:
P39359


Operon      
Name: yjhIHG         
Operon arrangement:
Transcription unit        Promoter
yjhIHG


Transcriptional Regulation      
Display Regulation             
Activated by: CRP


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yjhGp3 4524140 reverse Similarity to the consensus
Read more >
[ICWHO] [5]
  promoter yjhGp4 4524226 reverse Similarity to the consensus
Read more >
[ICWHO] [5]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Cabulong RB., Lee WK., Banares AB., Ramos KRM., Nisola GM., Valdehuesa KNG., Chung WJ., 2018, Engineering Escherichia coli for glycolic acid production from D-xylose through the Dahms pathway and glyoxylate bypass., Appl Microbiol Biotechnol 102(5):2179-2189

 [2] Gao H., Gao Y., Dong R., 2017, Enhanced biosynthesis of 3,4-dihydroxybutyric acid by engineered Escherichia coli in a dual-substrate system., Bioresour Technol 245(Pt A):794-800

 [3] Tai YS., Xiong M., Jambunathan P., Wang J., Stapleton C., Zhang K., 2016, Engineering nonphosphorylative metabolism to generate lignocellulose-derived products., Nat Chem Biol 12(4):247-53

 [4] Zhang N., Wang J., Zhang Y., Gao H., 2016, Metabolic pathway optimization for biosynthesis of 1,2,4-butanetriol from xylose by engineered Escherichia coli., Enzyme Microb Technol 93-94:51-58

 [5] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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