RegulonDB RegulonDB 11.1: Gene Form
   

feaB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

tynA feaB feaR FeaR FeaR CRP QseB Nac PhoB QseB NsrR feaBp1 feaBp1 feaRp3 feaRp3 feaBp2 feaBp2 feaRp feaRp feaRp1 feaRp1 feaRp2 feaRp2

Gene      
Name: feaB    Texpresso search in the literature
Synonym(s): ECK1382, G7961, b1385, padA, ydbG
Genome position(nucleotides): 1447519 --> 1449018
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.4
External database links:  
ASAP:
 ABE-0004637
ECHOBASE:
 EB2971
ECOLIHUB:
 feaB
OU-MICROARRAY:
 b1385
STRING:
 511145.b1385
COLOMBOS: feaB


Product      
Name: phenylacetaldehyde dehydrogenase
Synonym(s): FeaB, PadA, YdbG
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 53.699
Isoelectric point: 5.194
Motif(s):
 
Type Positions Sequence Comment
33 -> 495 SEKRLAIFDPATGQEIASTADANEADVDNAVMSAWRAFVSRRWAGRLPAERERILLRFADLVEQHSEELAQLETLEQGKSIAISRAFEVGCTLNWMRYTAGLTTKIAGKTLDLSIPLPQGARYQAWTRKEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELASEAGIPDGVFNVVTGSGAVCGAALTSHPHVAKISFTGSTATGKGIARTAADHLTRVTLELGGKNPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLFDTLVSGFEQAVKSLQVGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPAGEGYYVAPTLVVNPDAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQNLSQALEYSDRLQAGTVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSV
250 -> 255 GSTATG UniProt: NAD.
265 -> 265 H UniProt: In Ref. 3; CAA66106..
484 -> 499 DWLDGWCETKSVCVRY UniProt: In Ref. 1; CAA67780..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.4 - amines
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.3 - cofactors, small molecule carriers --> 1.5.3.7 - nicotinamide adenine dinucleotide
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0032991 - protein-containing complex
molecular_function GO:0016491 - oxidoreductase activity
GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0008957 - phenylacetaldehyde dehydrogenase activity
GO:0047106 - 4-hydroxyphenylacetaldehyde dehydrogenase activity
biological_process GO:0009435 - NAD biosynthetic process
GO:0046196 - 4-nitrophenol catabolic process
GO:0019607 - phenylethylamine catabolic process
GO:0006559 - L-phenylalanine catabolic process
External database links:  
ALPHAFOLD:
 P80668
DIP:
 DIP-9581N
ECOCYC:
 PHENDEHYD-MONOMER
ECOLIWIKI:
 b1385
INTERPRO:
 IPR029510
INTERPRO:
 IPR016163
INTERPRO:
 IPR016162
INTERPRO:
 IPR016161
INTERPRO:
 IPR015590
INTERPRO:
 IPR016160
MODBASE:
 P80668
PFAM:
 PF00171
PRIDE:
 P80668
PRODB:
 PRO_000022589
PROSITE:
 PS00070
PROSITE:
 PS00687
REFSEQ:
 NP_415903
SMR:
 P80668
UNIPROT:
 P80668


Operon      
Name: feaB         
Operon arrangement:
Transcription unit        Promoter
feaB
feaB


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FeaR
Repressed by: NsrR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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