RegulonDB RegulonDB 11.1: Gene Form
   

mgtL gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

mgtA treR mgtL PhoP ArcA Cis-reg; riboswitch mgtAp1 mgtAp1 TSS_5086 TSS_5086 treRp4 treRp4 TSS_5085 TSS_5085 mgtAp2 mgtAp2 treRp3 treRp3 treRp2 treRp2 treRp1 treRp1

Gene      
Name: mgtL    Texpresso search in the literature
Synonym(s): ECK4513, G0-10689, b4702
Genome position(nucleotides): 4467431 --> 4467484
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 50.0
External database links:  
ASAP:
 ABE-0285267
STRING:
 511145.b4702
COLOMBOS: mgtL


Product      
Name: leader peptide MgtL
Synonym(s): MgtL
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 2.123
Isoelectric point: 12.047
Motif(s):
 
Type Positions Sequence Comment
1 -> 17 MEPDPTPLPRRRLKLFR

 
Classification:
Multifun Terms (GenProtEC)  
  3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level
Gene Ontology Terms (GO)  
biological_process GO:0031556 - transcriptional attenuation by ribosome
GO:0032026 - response to magnesium ion
Note(s): Note(s): ...[more].
Evidence: [EXP-IDA] Inferred from direct assay
Reference(s): [1] Chadani Y., et al., 2017
External database links:  
ALPHAFOLD:
 E2JKY7
ECOCYC:
 MONOMER0-4201
INTERPRO:
 IPR031434
PFAM:
 PF17059
PRIDE:
 E2JKY7
REFSEQ:
 YP_003933616
UNIPROT:
 E2JKY7


Operon      
Name: mgtLA         
Operon arrangement:
Transcription unit        Promoter
mgtA
mgtA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_5085 4467343 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_5086 4467362 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Chadani Y., Niwa T., Izumi T., Sugata N., Nagao A., Suzuki T., Chiba S., Ito K., Taguchi H., 2017, Intrinsic Ribosome Destabilization Underlies Translation and Provides an Organism with a Strategy of Environmental Sensing., Mol Cell 68(3):528-539.e5

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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