Gene
Name:	hemB
Synonym(s):	ECK0366, EG10428, b0369, ncf
Genome position(nucleotides):	388753 <-- 389727
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.95
External database links:

ASAP:	ABE-0001266
CGSC:	647
ECHOBASE:	EB0423
ECOLIHUB:	hemB
MIM:	125270
MIM:	612740
OU-MICROARRAY:	b0369
STRING:	511145.b0369
COLOMBOS:	hemB

Reference(s)
[1] Adler H., Mural R., Suttle B., 1992, Oxygen sensitivity of an Escherichia coli mutant., J Bacteriol 174(7):2072-7
[2] Brana H., Hubacek J., Michaljanicova D., Holubova I., Cejka K., 1977, Membrane mutation affecting energy-linked functions in Escherichia coli K 12., Folia Microbiol (Praha) 22(3):198-205
[3] Cheung KM., Spencer P., Timko MP., Shoolingin-Jordan PM., 1997, Characterization of a recombinant pea 5-aminolevulinic acid dehydratase and comparative inhibition studies with the Escherichia coli dehydratase., Biochemistry 36(5):1148-56
[4] Echelard Y., Dymetryszyn J., Drolet M., Sasarman A., 1988, Nucleotide sequence of the hemB gene of Escherichia coli K12., Mol Gen Genet 214(3):503-8
[5] Erskine PT., Senior N., Maignan S., Cooper J., Lambert R., Lewis G., Spencer P., Awan S., Warren M., Tickle IJ., Thomas P., Wood SP., Shoolingin-Jordan PM., 1997, Crystallization of 5-aminolaevulinic acid dehydratase from Escherichia coli and Saccharomyces cerevisiae and preliminary X-ray characterization of the crystals., Protein Sci 6(8):1774-6
[6] Lewis LA., Gopaul S., Marsh C., 1994, The non-random pattern of insertion of IS2 into the hemB gene of Escherichia coli., Microbiol Immunol 38(6):461-5
[7] Lewis LA., Lewis D., Persaud V., Gopaul S., Turner B., 1994, Transposition of IS2 into the hemB gene of Escherichia coli K-12., J Bacteriol 176(7):2114-20
[8] Li F., Wang Y., Gong K., Wang Q., Liang Q., Qi Q., 2014, Constitutive expression of RyhB regulates the heme biosynthesis pathway and increases the 5-aminolevulinic acid accumulation in Escherichia coli., FEMS Microbiol Lett 350(2):209-15
[9] Li JM., Russell CS., Cosloy SD., 1989, The structure of the Escherichia coli hemB gene., Gene 75(1):177-84
[10] Li JM., Umanoff H., Proenca R., Russell CS., Cosloy SD., 1988, Cloning of the Escherichia coli K-12 hemB gene., J Bacteriol 170(2):1021-5
[11] Lin J., Fu W., Cen P., 2009, Characterization of 5-aminolevulinate synthase from Agrobacterium radiobacter, screening new inhibitors for 5-aminolevulinate dehydratase from Escherichia coli and their potential use for high 5-aminolevulinate production., Bioresour Technol 100(7):2293-7
[12] Norton E., Sarwar M., Shoolingin-Jordan P., 1998, Mechanistic studies on E.coli 5-aminolaevulinic acid dehydratase., Biochem Soc Trans 26(3):S285
[13] O'Neill GP., Thorbjarnardottir S., Michelsen U., Palsson S., Soll D., Eggertsson G., 1991, delta-Aminolevulinic acid dehydratase deficiency can cause delta-aminolevulinate auxotrophy in Escherichia coli., J Bacteriol 173(1):94-100
[14] Philipp-Dormston WK., Doss M., 1975, Over-production of porphyrins and heme in heterotrophic bacteria., Z Naturforsch C 30(3):425-6
[15] Shimoni-Livny L., Carrell HL., Wagner T., Kaufman Katz A., Afshar C., Mitchell LW., Volin M., Jaffe EK., Glusker JP., 1998, Crystallization and preliminary X-ray diffraction studies of E. coli porphobilinogen synthase and its heavy-atom derivatives., Acta Crystallogr D Biol Crystallogr 54(Pt 3):438-40
[16] Spencer P., Jordan PM., 1994, 5-Aminolaevulinic acid dehydratase: characterization of the alpha and beta metal-binding sites of the Escherichia coli enzyme., Ciba Found Symp 180:50-64: discussion 64-9
[17] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78