RegulonDB RegulonDB 10.8: Gene Form
   

gatY gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gatZ fbaB gatY CRP terminator gatYp gatYp TSS_2434 TSS_2434 TSS_2433 TSS_2433 TSS_2432 TSS_2432 TSS_2431 TSS_2431 TSS_2430 TSS_2430 TSS_2429 TSS_2429 TSS_2428 TSS_2428 TSS_2427 TSS_2427 TSS_2426 TSS_2426 TSS_2425 TSS_2425 TSS_2424 TSS_2424 TSS_2423 TSS_2423 TSS_2422 TSS_2422 TSS_2421 (cluster) TSS_2421 (cluster) gatZp gatZp TSS_2419 (cluster) TSS_2419 (cluster) TSS_2418 TSS_2418 TSS_2417 TSS_2417 TSS_2416 TSS_2416 TSS_2415 TSS_2415 TSS_2414 TSS_2414

Gene      
Name: gatY    Texpresso search in the literature
Synonym(s): ECK2089, EG12419, b2096, yegF
Genome position(nucleotides): 2176350 <-- 2177204 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.1
Reference(s): [1] Hollands K., et al., 2007
External database links:  
ASAP:
ABE-0006938
ECHOBASE:
EB2318
OU-MICROARRAY:
b2096
PortEco:
gatY
STRING:
511145.b2096
COLOMBOS: gatY


Product      
Name: tagatose-1,6-bisphosphate aldolase 2 subunit GatY
Synonym(s): GatY, YegF
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 30.812
Isoelectric point: 6.313
Motif(s):
 
Type Positions Sequence
4 -> 283 VSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGR
209 -> 211 GAS
230 -> 233 NVAT

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0003824 - catalytic activity
GO:0005515 - protein binding
GO:0016829 - lyase activity
GO:0046872 - metal ion binding
GO:0016832 - aldehyde-lyase activity
GO:0008270 - zinc ion binding
GO:0009025 - tagatose-bisphosphate aldolase activity
biological_process GO:0005975 - carbohydrate metabolic process
GO:0019402 - galactitol metabolic process
GO:0019404 - galactitol catabolic process
GO:2001059 - D-tagatose 6-phosphate catabolic process
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-48239N
ECOCYC:
TAGAALDOL2-MONOMER
ECOLIWIKI:
b2096
INTERPRO:
IPR023955
INTERPRO:
IPR013785
INTERPRO:
IPR011288
INTERPRO:
IPR000771
MINT:
MINT-1266244
MODBASE:
P37192
PFAM:
PF01116
PRIDE:
P0C8J6
PROSITE:
PS00602
PROSITE:
PS00806
REFSEQ:
NP_416599
SMR:
P0C8J6
SWISSMODEL:
P37192
UNIPROT:
P0C8J6


Operon      
Name: gatYZABCD         
Operon arrangement:
Transcription unit        Promoter
gatZABCD
gatYZABCD


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: ArcA, GatR


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2414 2175103 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2415 2175270 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2416 2175336 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2417 2176110 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2418 2176118 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2419 (cluster) 2176382 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_2421 (cluster) 2176636 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_2422 2176657 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2423 2176773 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2424 2176779 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2425 2176864 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2426 2177023 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2427 2177046 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2428 2177069 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2429 2177071 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2430 2177123 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2431 2177200 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2432 2177204 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2433 2177212 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2434 2177228 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Hollands K., Busby SJ., Lloyd GS., 2007, New targets for the cyclic AMP receptor protein in the Escherichia coli K-12 genome., FEMS Microbiol Lett 274(1):89-94

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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