RegulonDB RegulonDB 11.1: Gene Form
   

ybhK gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

uvrB moaA ybhK CueR ModE FNR Cis-reg; riboswitch TSS_948 (cluster) TSS_948 (cluster) moaBp moaBp moaAp2 moaAp2 TSS_945 (cluster) TSS_945 (cluster) TSS_944 TSS_944 moaAp1 moaAp1 ybhKp ybhKp TSS_942 (cluster) TSS_942 (cluster)

Gene      
Name: ybhK    Texpresso search in the literature
Synonym(s): ECK0769, G6402, b0780
Genome position(nucleotides): 815739 <-- 816647
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.38
External database links:  
ASAP:
 ABE-0002661
ECHOBASE:
 EB3431
ECOLIHUB:
 ybhK
OU-MICROARRAY:
 b0780
STRING:
 511145.b0780
COLOMBOS: ybhK


Product      
Name: putative transferase YbhK
Synonym(s): YbhK, putative transferase with NAD(P)-binding Rossmann-fold domain
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 32.788
Isoelectric point: 6.427
Motif(s):
 
Type Positions Sequence Comment
12 -> 289 VVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLKALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTPIQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMVYIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVLEASDIPYRHDRQL

 
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0043743 - LPPG:FO 2-phospho-L-lactate transferase activity
GO:0005515 - protein binding
biological_process GO:0008360 - regulation of cell shape
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P75767
DIP:
 DIP-11414N
ECOCYC:
 G6402-MONOMER
ECOLIWIKI:
 b0780
INTERPRO:
 IPR010119
INTERPRO:
 IPR002882
INTERPRO:
 IPR038136
PANTHER:
 PTHR30135
PFAM:
 PF01933
PRIDE:
 P75767
REFSEQ:
 NP_415301
SMR:
 P75767
UNIPROT:
 P75767


Operon      
Name: ybhK         
Operon arrangement:
Transcription unit        Promoter
ybhK


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_942 (cluster) 816671 reverse nd [RS-EPT-CBR] [1]
  promoter ybhKp 816692 reverse We assigned a putative transcription
Read more > 		[COMP-AINF], [COMP-AINF-POSITIONAL-IDENTIFICATION], [COMP-AINF-SIMILAR-TO-CONSENSUS] [2], [3]
  promoter TSS_944 816830 forward nd [RS-EPT-CBR] [1]
  promoter TSS_945 (cluster) 816858 forward nd [RS-EPT-CBR] [1]
  promoter TSS_948 (cluster) 818012 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [COMP-AINF] Inferred computationally without human oversight

 [COMP-AINF-POSITIONAL-IDENTIFICATION] Automated inference of promoter position

 [COMP-AINF-SIMILAR-TO-CONSENSUS] Automated inference based on similarity to consensus sequences


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Reitzer L., Schneider BL., 2001, Metabolic context and possible physiological themes of sigma(54)-dependent genes in Escherichia coli., Microbiol Mol Biol Rev 65(3):422-44, table of contents

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