RegulonDB RegulonDB 11.1: Gene Form
   

ydcV gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

patD ydcT ydcU ydcV patDp4 patDp4 patDp3 patDp3

Gene      
Name: ydcV    Texpresso search in the literature
Synonym(s): ECK1437, G6754, b1443
Genome position(nucleotides): 1514762 --> 1515556
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.96
External database links:  
ASAP:
ABE-0004809
ECHOBASE:
EB3528
ECOLIHUB:
ydcV
OU-MICROARRAY:
b1443
STRING:
511145.b1443
COLOMBOS: ydcV


Product      
Name: putative ABC transporter membrane subunit YdcV
Synonym(s): YdcV
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 28.722
Isoelectric point: 9.238
Motif(s):
 
Type Positions Sequence Comment
13 -> 33 AAWGGVVFLHFPILIIAAYAF UniProt: Helical.
65 -> 252 VTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAISLLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTSWSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTLPLWLLNQLGRPRDVPVTNVVALLVMLVTTLPILG UniProt: ABC transmembrane type-1.
71 -> 91 VAALATLIALVLGTLAAAALW UniProt: Helical.
80 -> 247 LVLGTLAAAALWRRDFFGKNAISLLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTSWSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTLPLWLLNQLGRPRDVPVTNVVALLVMLVTT
101 -> 121 ISLLLLLPIALPGIVTGLALL UniProt: Helical.

 

Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.1 - membrane
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.m - ABC superfamily, membrane component
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
biological_process GO:0055085 - transmembrane transport
GO:0009290 - DNA import into cell involved in transformation
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
[2] Moussatova A., et al., 2008
External database links:  
ALPHAFOLD:
P0AFR9
ECOCYC:
YDCV-MONOMER
ECOLIWIKI:
b1443
INTERPRO:
IPR035906
INTERPRO:
IPR000515
PFAM:
PF00528
PRIDE:
P0AFR9
PROSITE:
PS50928
REFSEQ:
NP_415960
UNIPROT:
P0AFR9


Operon      
Name: ydcSTUV-patD         
Operon arrangement:
Transcription unit        Promoter
ydcSTUV-patD
patD


Transcriptional Regulation      
Display Regulation             
Activated by: Nac


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter patDp3 1515415 forward nd [COMP-AINF] [3]
  promoter patDp4 1515440 forward nd [COMP-AINF] [3]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight



Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Moussatova A., Kandt C., O'Mara ML., Tieleman DP., 2008, ATP-binding cassette transporters in Escherichia coli., Biochim Biophys Acta 1778(9):1757-71

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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