RegulonDB RegulonDB 10.8: Gene Form
   

hcaT gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

csiE hcaT hcaR yfhR iroK CRP terminator hcaTp7 hcaTp7 hcaTp6 hcaTp6 hcaTp1 hcaTp1 csiEp csiEp

Gene      
Name: hcaT    Texpresso search in the literature
Synonym(s): ECK2533, G7330, b2536, yfhS
Genome position(nucleotides): 2666707 <-- 2667846 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
56.49
External database links:  
ASAP:
ABE-0008348
ECHOBASE:
EB3227
OU-MICROARRAY:
b2536
PortEco:
hcaT
STRING:
511145.b2536
COLOMBOS: hcaT


Product      
Name: putative 3-phenylpropionate transporter
Synonym(s): HcaT, YfhS
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 41.593
Isoelectric point: 10.116
Motif(s):
 
Type Positions Sequence
5 -> 31 STRWLALGYFTYFFSYGIFLPFWSVWL
8 -> 358 WLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLLLGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIGFNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVTMFDYRVILALLTLGVASMLLGFLIRPTIQPQGASRQQESTGWSAWLALVRQNWRFLACVCLLQGAHAAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAICGVVRWGIMGATTALPWLIVVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQYLGHGVF
38 -> 66 PETIGLLLGAGLVARFLGSLLIAPRVSDP
232 -> 256 AGYSASAVGYLWSLGVVAEVIIFAL
156 -> 175 YRVILALLTLGVASMLLGFL

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015293 - symporter activity
GO:0015528 - lactose:proton symporter activity
GO:0030395 - lactose binding
biological_process GO:0055085 - transmembrane transport
GO:0015767 - lactose transport
GO:0071702 - organic substance transport
Note(s): Note(s): ...[more].
Reference(s): [1] Burlingame R., et al., 1983
[2] Riley M., et al., 2006
External database links:  
ECOCYC:
HCAT-MONOMER
ECOLIWIKI:
b2536
INTERPRO:
IPR026032
INTERPRO:
IPR036259
INTERPRO:
IPR024989
MODBASE:
Q47142
PFAM:
PF12832
PRIDE:
Q47142
REFSEQ:
NP_417031
SMR:
Q47142
UNIPROT:
Q47142


Operon      
Name: hcaT         
Operon arrangement:
Transcription unit        Promoter
 


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter hcaTp1 2667863 reverse Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter hcaTp6 2667928 reverse Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter hcaTp7 2668053 reverse Similarity to the consensus
Read more >
[ICWHO] [3]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Burlingame R., Chapman PJ., 1983, Catabolism of phenylpropionic acid and its 3-hydroxy derivative by Escherichia coli., J Bacteriol 155(1):113-21

 [2] Riley M., Abe T., Arnaud MB., Berlyn MK., Blattner FR., Chaudhuri RR., Glasner JD., Horiuchi T., Keseler IM., Kosuge T., Mori H., Perna NT., Plunkett G., Rudd KE., Serres MH., Thomas GH., Thomson NR., Wishart D., Wanner BL., 2006, Escherichia coli K-12: a cooperatively developed annotation snapshot--2005., Nucleic Acids Res 34(1):1-9

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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