RegulonDB RegulonDB 10.8: Gene Form
   

araD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

polB araA araD LexA anti-anti-terminator anti-terminator terminator terminator polBp polBp hepAp2 hepAp2 TSS_118 TSS_118

Gene      
Name: araD    Texpresso search in the literature
Synonym(s): ECK0062, EG10055, b0061
Genome position(nucleotides): 65855 <-- 66550 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.32
External database links:  
ASAP:
ABE-0000209
CGSC:
1025
ECHOBASE:
EB0053
OU-MICROARRAY:
b0061
PortEco:
araD
STRING:
511145.b0061
COLOMBOS: araD


Product      
Name: L-ribulose-5-phosphate 4-epimerase AraD
Synonym(s): AraD
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 25.519
Isoelectric point: 6.109
Motif(s):
 
Type Positions Sequence
42 -> 42 K
76 -> 76 D
229 -> 229 Y
28 -> 28 N
95 -> 95 H

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0032991 - protein-containing complex
molecular_function GO:0016853 - isomerase activity
GO:0046872 - metal ion binding
GO:0016832 - aldehyde-lyase activity
GO:0008270 - zinc ion binding
GO:0008742 - L-ribulose-phosphate 4-epimerase activity
GO:0042802 - identical protein binding
biological_process GO:0005975 - carbohydrate metabolic process
GO:0019323 - pentose catabolic process
GO:0019568 - arabinose catabolic process
GO:0019324 - L-lyxose metabolic process
GO:0019569 - L-arabinose catabolic process to xylulose 5-phosphate
GO:0019572 - L-arabinose catabolic process
GO:0051289 - protein homotetramerization
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-9126N
ECOCYC:
RIBULPEPIM-MONOMER
ECOLIWIKI:
b0061
INTERPRO:
IPR004661
INTERPRO:
IPR036409
INTERPRO:
IPR033748
INTERPRO:
IPR001303
MODBASE:
P08203
PDB:
1JDI
PDB:
1K0W
PFAM:
PF00596
PRIDE:
P08203
PRODB:
PRO_000022117
REFSEQ:
NP_414603
SMART:
SM01007
SMR:
P08203
UNIPROT:
P08203


Operon      
Name: araBAD         
Operon arrangement:
Transcription unit        Promoter
araBAD


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, AraC
Repressed by: AraC


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_118 63450 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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