RegulonDB RegulonDB 10.8: Gene Form
   

araE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

araE kduD ygeA lysR CRP AraC AraC anti-anti-terminator anti-terminator terminator anti-anti-terminator anti-terminator terminator araEp araEp ygeAp5 ygeAp5

Gene      
Name: araE    Texpresso search in the literature
Synonym(s): ECK2839, EG10056, b2841
Genome position(nucleotides): 2980764 <-- 2982182 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.16
External database links:  
ASAP:
ABE-0009319
CGSC:
1024
ECHOBASE:
EB0054
OU-MICROARRAY:
b2841
PortEco:
araE
STRING:
511145.b2841
COLOMBOS: araE


Shine dalgarno      
Sequence: tctctgctggCAGGAAaaAAT


Product      
Name: arabinose:H+ symporter
Synonym(s): AraE, arabinose MFS transporter
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 51.684
Isoelectric point: 9.75
Motif(s):
 
Type Positions Sequence
30 -> 50 AVAGLLFGLDIGVIAGALPFI
64 -> 84 VVSSMMLGAAIGALFNGWLSF
258 -> 278 AVFLGMLLQAMQQFTGMNIIM
115 -> 135 LIAARVVLGIAVGIASYTAPL
326 -> 346 ALKIGFSVMALGTLVLGYCLM

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015293 - symporter activity
GO:0005351 - carbohydrate:proton symporter activity
GO:0015150 - fucose transmembrane transporter activity
GO:0022857 - transmembrane transporter activity
GO:0015147 - L-arabinose transmembrane transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0015756 - fucose transmembrane transport
GO:0055085 - transmembrane transport
GO:0042882 - L-arabinose transmembrane transport
GO:0046323 - glucose import
GO:1902600 - proton transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Maiden MC., et al., 1988
External database links:  
ECOCYC:
ARAE-MONOMER
ECOLIWIKI:
b2841
INTERPRO:
IPR020846
INTERPRO:
IPR036259
INTERPRO:
IPR005829
INTERPRO:
IPR005828
INTERPRO:
IPR003663
MODBASE:
P0AE24
PFAM:
PF00083
PRIDE:
P0AE24
PRINTS:
PR00171
PRODB:
PRO_000022118
PROSITE:
PS50850
PROSITE:
PS00216
PROSITE:
PS00217
REFSEQ:
NP_417318
SMR:
P0AE24
UNIPROT:
P0AE24


Operon      
Name: araE-ygeA         
Operon arrangement:
Transcription unit        Promoter
araE
araE-ygeA
 


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, AraC


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ygeAp5 2980803 reverse Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Maiden MC., Jones-Mortimer MC., Henderson PJ., 1988, The cloning, DNA sequence, and overexpression of the gene araE coding for arabinose-proton symport in Escherichia coli K12., J Biol Chem 263(17):8003-10

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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