RegulonDB RegulonDB 10.8: Gene Form
   

argT gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

argT hisJ ubiX NtrC NtrC ArgR ArgR GcvB ppGpp TSS_2620 TSS_2620 argTp argTp hisJp hisJp TSS_2618 TSS_2618

Gene      
Name: argT    Texpresso search in the literature
Synonym(s): ECK2304, EG10072, b2310
Genome position(nucleotides): 2427009 <-- 2427791 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
50.19
External database links:  
ASAP:
ABE-0007621
CGSC:
18529
ECHOBASE:
EB0070
OU-MICROARRAY:
b2310
PortEco:
argT
STRING:
511145.b2310
COLOMBOS: argT


Product      
Name: lysine/arginine/ornithine ABC transporter periplasmic binding protein
Synonym(s): ArgT
Sequence: Get amino acid sequence Fasta Format
Cellular location: periplasmic space
Molecular weight: 27.992
Isoelectric point: 5.461
Motif(s):
 
Type Positions Sequence
213 -> 213 F
86 -> 87 ID
200 -> 201 FA
237 -> 239 GEL
1 -> 22 MKKSILALSLLVGLSTAASSYA

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.3 - arginine
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.7 - lysine
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.p - ABC superfamily, periplasmic binding component
Gene Ontology Terms (GO)  
cellular_component GO:0030288 - outer membrane-bounded periplasmic space
GO:0042597 - periplasmic space
biological_process GO:0006865 - amino acid transport
GO:0009267 - cellular response to starvation
GO:0071705 - nitrogen compound transport
GO:0071294 - cellular response to zinc ion
GO:0006995 - cellular response to nitrogen starvation
GO:0015822 - ornithine transport
GO:1902022 - L-lysine transport
GO:1902023 - L-arginine transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-9148N
ECOCYC:
ARGT-MONOMER
ECOLIWIKI:
b2310
INTERPRO:
IPR005768
INTERPRO:
IPR001638
INTERPRO:
IPR018313
MODBASE:
P09551
PFAM:
PF00497
PRIDE:
P09551
PRODB:
PRO_000022136
PROSITE:
PS01039
REFSEQ:
NP_416813
SMART:
SM00062
SMR:
P09551
SWISSMODEL:
P09551
UNIPROT:
P09551


Operon      
Name: argT-hisJQMP         
Operon arrangement:
Transcription unit        Promoter
hisJQMP
argT-hisJQMP


Transcriptional Regulation      
Display Regulation             
Activated by: NtrC


Regulation by small RNA    
  Display Regulation
small RNA gcvB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2618 2426821 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2620 2427937 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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