RegulonDB RegulonDB 11.1: Gene Form
   

moeB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

moeA iaaA moeB fsaA gsiA NarL ArcA NarL FNR anti-anti-terminator anti-terminator terminator iaaAp iaaAp moeAp moeAp

Gene      
Name: moeB    Texpresso search in the literature
Synonym(s): ECK0816, EG10154, b0826, chlN
Genome position(nucleotides): 864380 <-- 865129
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.2
External database links:  
ASAP:
 ABE-0002820
CGSC:
 18472
ECHOBASE:
 EB0152
ECOLIHUB:
 moeB
OU-MICROARRAY:
 b0826
STRING:
 511145.b0826
COLOMBOS: moeB


Product      
Name: molybdopterin-synthase adenylyltransferase
Synonym(s): ChlN, MoeB
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 26.719
Isoelectric point: 4.673
Motif(s):
 
Type Positions Sequence Comment
12 -> 245 YNRQIILRGFDFDGQEALKDSRVLIVGLGGLGCAASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIAITPVNALLDDAELAALIAEHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKMLAGYGKPASGKIVMYDAMTCQFREMKLMRNPGCE
14 -> 14 R UniProt: No effect..
44 -> 44 C UniProt: No effect..
69 -> 73 SNLQR UniProt: ATP.
73 -> 73 R UniProt: No effect. No activity; when associated with A-14..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.3 - cofactors, small molecule carriers --> 1.5.3.4 - molybdenum
Gene Ontology Terms (GO)  
cellular_component GO:1990133 - molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex
GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0016779 - nucleotidyltransferase activity
GO:0005515 - protein binding
GO:0016740 - transferase activity
GO:0046872 - metal ion binding
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0042803 - protein homodimerization activity
GO:0061605 - molybdopterin-synthase adenylyltransferase activity
GO:0008641 - ubiquitin-like modifier activating enzyme activity
biological_process GO:0006777 - Mo-molybdopterin cofactor biosynthetic process
External database links:  
ALPHAFOLD:
 P12282
DIP:
 DIP-10241N
ECOCYC:
 EG10154-MONOMER
ECOLIWIKI:
 b0826
INTERPRO:
 IPR035985
INTERPRO:
 IPR012730
INTERPRO:
 IPR000594
MODBASE:
 P12282
PDB:
 1JWB
PDB:
 1JWA
PDB:
 1JW9
PFAM:
 PF00899
PRIDE:
 P12282
REFSEQ:
 NP_415347
SMR:
 P12282
UNIPROT:
 P12282


Operon      
Name: moeAB         
Operon arrangement:
Transcription unit        Promoter
moeAB


Transcriptional Regulation      
Display Regulation             
Activated by: NsrR, NarL, ArcA
Repressed by: FNR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB