RegulonDB RegulonDB 10.6.3: Gene Form
   

cysE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gpsA cysE trmL RyhB TSS_4185 TSS_4185 TSS_4184 TSS_4184 TSS_4183 (cluster) TSS_4183 (cluster) cysEp cysEp

Gene      
Name: cysE    Texpresso search in the literature
Synonym(s): ECK3597, EG10187, b3607
Genome position(nucleotides): 3781741 <-- 3782562 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.53
External database links:  
ASAP:
ABE-0011793
CGSC:
894
ECHOBASE:
EB0184
ECOCYC:
EG10187
ECOLIHUB:
cysE
OU-MICROARRAY:
b3607
REGULONDB:
b3607
STRING:
511145.b3607
M3D: cysE
COLOMBOS: cysE
PortEco: b3607


Product      
Name: serine acetyltransferase
Synonym(s): CysE
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 29.317
Isoelectric point: 6.504
Motif(s):
 
Type Positions Sequence
193 -> 226 HPKIREGVMIGAGAKILGNIEVGRGAKIGAGSVV
9 -> 113 VWNNIKAEARTLADCEPMLASFYHATLLKHENLGSALSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPLLYLKGFHALQA

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.12 - cysteine
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009333 - cysteine synthase complex
molecular_function GO:0005515 - protein binding
GO:0016740 - transferase activity
GO:0016746 - transferase activity, transferring acyl groups
GO:0009001 - serine O-acetyltransferase activity
GO:0016412 - serine O-acyltransferase activity
biological_process GO:0010165 - response to X-ray
GO:0008652 - cellular amino acid biosynthetic process
GO:0019344 - cysteine biosynthetic process
GO:0006535 - cysteine biosynthetic process from serine
External database links:  
DIP:
DIP-9377N
ECOCYC:
SERINE-O-ACETTRAN-MONOMER
ECOLIWIKI:
b3607
INTERPRO:
IPR010493
INTERPRO:
IPR018357
INTERPRO:
IPR011004
INTERPRO:
IPR005881
INTERPRO:
IPR001451
MODBASE:
P0A9D4
PDB:
1T3D
PFAM:
PF00132
PFAM:
PF06426
PRIDE:
P0A9D4
PRODB:
PRO_000022377
PROSITE:
PS00101
PROTEINMODELPORTAL:
P0A9D4
REFSEQ:
NP_418064
SMART:
SM00971
SMR:
P0A9D4
UNIPROT:
P0A9D4


Operon      
Name: cysE         
Operon arrangement:
Transcription unit        Promoter
cysE


Transcriptional Regulation      
Display Regulation             
Repressed by: SutR


Regulation by small RNA    
  Display Regulation
small RNA ryhB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4183 (cluster) 3783637 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter TSS_4184 3783640 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4185 3783644 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Mu¿¿iz-Rascado L, Garc¿¿a-Sotelo JS, Weiss V, Solano-Lira H, Mart¿¿nez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hern¿¿ndez S, Alquicira-Hern¿¿ndez K, L¿¿pez-Fuentes A, Porr¿¿n-Sotelo L, Huerta AM, Bonavides-Mart¿¿nez C, Balderas-Mart¿¿nez YI, Pannier L, Olvera M, Labastida A, Jim¿¿nez-Jacinto V, Vega-Alvarado L, Del Moral-Ch¿¿vez V, Hern¿¿ndez-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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