RegulonDB RegulonDB 11.1: Gene Form
   

dmsC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

dmsC ycaC dmsB dmsCp dmsCp

Gene      
Name: dmsC    Texpresso search in the literature
Synonym(s): ECK0887, EG10234, b0896
Genome position(nucleotides): 944033 --> 944896
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.63
External database links:  
ASAP:
 ABE-0003048
CGSC:
 31727
ECHOBASE:
 EB0230
ECOLIHUB:
 dmsC
OU-MICROARRAY:
 b0896
STRING:
 511145.b0896
COLOMBOS: dmsC


Product      
Name: dimethyl sulfoxide reductase subunit C
Synonym(s): DmsC, dimethyl sulfoxide reductase, chain C
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 30.826
Isoelectric point: 9.18
Motif(s):
 
Type Positions Sequence Comment
1 -> 277 MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRVIACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGWLLAMLKKLSPALRTLWLIVTMVLGVIFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMFMGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVVSVMQGAELATIHSSVQQAAALVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYGL
10 -> 32 LMIFTVFGQCVAGGFIVLALALL UniProt: Helical.
44 -> 66 VIACMFGLWVLMGIGFIASMLHL UniProt: Helical.
87 -> 87 E alternate sequence E87K and E87 D; mutant protein cannot support anaerobic growth on glycerol/DMSO minimal media; possible role in menaquinol binding
90 -> 107 SGSIFFAVGGIGWLLAML UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.7 - anaerobic respiration
  1 - metabolism --> 1.4 - energy production/transport --> 1.4.2 - electron acceptors
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0009390 - dimethyl sulfoxide reductase complex
molecular_function GO:0016491 - oxidoreductase activity
GO:0009389 - dimethyl sulfoxide reductase activity
biological_process GO:0018907 - dimethyl sulfoxide metabolic process
GO:0009061 - anaerobic respiration
GO:0019645 - anaerobic electron transport chain
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P18777
ECOCYC:
 DMSC-MONOMER
ECOLIWIKI:
 b0896
INTERPRO:
 IPR007059
PANTHER:
 PTHR38095
PFAM:
 PF04976
PRIDE:
 P18777
PRODB:
 PRO_000022457
REFSEQ:
 NP_415416
UNIPROT:
 P18777


Operon      
Name: dmsABC         
Operon arrangement:
Transcription unit        Promoter
dmsABC
dmsABC
dmsC


Transcriptional Regulation      
Display Regulation             
Activated by: FNR
Repressed by: IHF, NarL, ModE, Fis


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB