RegulonDB RegulonDB 10.7: Gene Form
   

dsdX gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

dsdX dsdA dsdC NsrR CRP CRP TSS_2664 TSS_2664 dsdAp dsdAp TSS_2663 TSS_2663 dsdXp dsdXp dsdCp dsdCp

Gene      
Name: dsdX    Texpresso search in the literature
Synonym(s): ECK2361, EG10250, b2365, dsdC, yfdA, yfdD
Genome position(nucleotides): 2477847 --> 2479184 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
48.73
External database links:  
ASAP:
ABE-0007801
CGSC:
35717
ECHOBASE:
EB0246
ECOO157CYC:
Z3627
OU-MICROARRAY:
b2365
PORTECO:
dsdX
REGULONDB:
b2365
STRING:
511145.b2365
M3D: dsdX
COLOMBOS: dsdX
PortEco: b2365


Product      
Name: D-serine transporter
Synonym(s): DsdC, DsdX, YfdA, YfdD
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 47.163
Isoelectric point: 8.141
Motif(s):
 
Type Positions Sequence
57 -> 77 SGIGGTLGFLAAVIGLGTILG
385 -> 405 IIAIAIGSGAIGCTIVTDSLF
258 -> 278 LYILVEFIGNPITAMFIAVFV
302 -> 322 FGSIANILLIIGAGGAFNAIL
7 -> 444 VVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSVDVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTILLPIALMLVKTIAELNMARESGLYILVEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFI

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015128 - gluconate transmembrane transporter activity
GO:0042945 - D-serine transmembrane transporter activity
biological_process GO:0006974 - cellular response to DNA damage stimulus
GO:0006865 - amino acid transport
GO:0035429 - gluconate transmembrane transport
GO:0042942 - D-serine transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-9481N
ECOCYC:
DSDX-MONOMER
ECOLIWIKI:
b2365
ECOO157CYC:
Z3627-MONOMER
INTERPRO:
IPR003474
MINT:
MINT-1235614
PANTHER:
PTHR30354
PFAM:
PF02447
PRIDE:
P08555
PRODB:
PRO_000022487
PROTEINMODELPORTAL:
P08555
REFSEQ:
NP_416866
UNIPROT:
P08555


Operon      
Name: dsdXA         
Operon arrangement:
Transcription unit        Promoter
dsdXA
dsdA


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, DsdC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2663 2479114 forward nd [RS-EPT-CBR] [1]
  promoter TSS_2664 2480013 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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