RegulonDB RegulonDB 10.7: Gene Form
   

edd gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

Gene      
Name: edd    Texpresso search in the literature
Synonym(s): ECK1852, EG10257, b1851
Genome position(nucleotides): 1932793 <-- 1934604 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.64
Reference(s): [1] Carter AT., et al., 1993
[2] Conway T., et al., 1991
[3] Egan SE., et al., 1992
[4] Peyru G., et al., 1968
External database links:  
ASAP:
ABE-0006166
CGSC:
825
ECHOBASE:
EB0253
OU-MICROARRAY:
b1851
PORTECO:
edd
REGULONDB:
b1851
STRING:
511145.b1851
M3D: edd
COLOMBOS: edd
PortEco: b1851


Product      
Name: phosphogluconate dehydratase
Synonym(s): Edd
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 64.639
Isoelectric point: 6.351
Motif(s):
 
Type Positions Sequence
66 -> 598 NNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVGQVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPGLTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAPGTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWMPIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMARLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGELDWREGAEKSLDSNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVVFESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVTDGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAAREPHIPDLSASRVGTGRELFSALREKLSGAEQGA
252 -> 254 PLR

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.9 - Entner-Doudoroff
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0003824 - catalytic activity
GO:0016829 - lyase activity
GO:0046872 - metal ion binding
GO:0051536 - iron-sulfur cluster binding
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0004456 - phosphogluconate dehydratase activity
biological_process GO:0005975 - carbohydrate metabolic process
GO:0009255 - Entner-Doudoroff pathway through 6-phosphogluconate
GO:0019521 - D-gluconate metabolic process
GO:0046177 - D-gluconate catabolic process
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-47906N
ECOCYC:
PGLUCONDEHYDRAT-MONOMER
ECOLIWIKI:
b1851
INTERPRO:
IPR000581
INTERPRO:
IPR004786
INTERPRO:
IPR042096
INTERPRO:
IPR020558
INTERPRO:
IPR037237
PANTHER:
PTHR43661:SF1
PFAM:
PF00920
PRIDE:
P0ADF6
PRODB:
PRO_000022503
PROSITE:
PS00886
PROSITE:
PS00887
PROTEINMODELPORTAL:
P0ADF6
REFSEQ:
NP_416365
SMR:
P0ADF6
UNIPROT:
P0ADF6


Operon      
Name: edd-eda         
Operon arrangement:
Transcription unit        Promoter
eda
eda
eda
edd-eda


Transcriptional Regulation      
Display Regulation             
Repressed by: KdgR, Cra, GntR


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2191 1932530 reverse nd [RS-EPT-CBR] [5]
  promoter TSS_2192 1932726 reverse nd [RS-EPT-CBR] [5]
  promoter TSS_2193 1932744 reverse nd [RS-EPT-CBR] [5]
  promoter TSS_2196 1935229 reverse nd [RS-EPT-CBR] [5]
  promoter TSS_2197 1935719 reverse nd [RS-EPT-CBR] [5]



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