RegulonDB

Gene
Name:	fliL
Synonym(s):	ECK1942, EG10322, b1944, cheC1, flaAI, flaQI
Genome position(nucleotides):	2019618 --> 2020082 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.33
External database links:

ASAP:	ABE-0006467
CGSC:	18316
ECHOBASE:	EB0318
OU-MICROARRAY:	b1944
PortEco:	fliL
STRING:	511145.b1944
COLOMBOS:	fliL

Product

Name:

flagellar protein FliL

Synonym(s):

FliL

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane,cell projection

Molecular weight:

17.221

Isoelectric point:

9.326

Motif(s):

Type	Positions	Sequence
	56 -> 152	FYALDTFTVNLGDADRVLYIGITLRLKDEATRSRLSEYLPEVRSRLLLLFSRQDAAVLATEEGKKNLIAEIKTTLSTPLVAGQPKQDVTDVLYTAFI
	13 -> 35	SLWIPILVFITLAACASAGYSYW

Classification:

Multifun Terms (GenProtEC)
		5 - cell processes --> 5.3 - motility, chemotaxis, energytaxis (aerotaxis, redoxtaxis etc)
		6 - cell structure --> 6.4 - flagella
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane GO:0009425 - bacterial-type flagellum basal body
	molecular_function	GO:0042802 - identical protein binding
	biological_process	GO:0006935 - chemotaxis GO:0071973 - bacterial-type flagellum-dependent cell motility GO:0071978 - bacterial-type flagellum-dependent swarming motility GO:0097588 - archaeal or bacterial-type flagellum-dependent cell motility

Note(s):

Note(s): ...[more].

Evidence:

[IMP] Inferred from mutant phenotype

Reference(s):

[1] Attmannspacher U., et al., 2008
[2] Chawla R., et al., 2017
[3] Partridge JD., et al., 2015
[4] Suzuki T., et al., 1981

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PANTHER:

PFAM:

PRIDE:

PRODB:

REFSEQ:

UNIPROT:

Operon

Name:

fliLMNOPQR

Operon arrangement:

Transcription unit	Promoter
fliLMNOPQR	fliLp1
fliLMNOPQR	fliLp2

Transcriptional Regulation
	Display Regulation
Activated by:	FlhDC

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_2270	2020910		forward	nd	[RS-EPT-CBR]	[5]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Attmannspacher U., Scharf BE., Harshey RM., 2008, FliL is essential for swarming: motor rotation in absence of FliL fractures the flagellar rod in swarmer cells of Salmonella enterica., Mol Microbiol 68(2):328-41
[2] Chawla R., Ford KM., Lele PP., 2017, Torque, but not FliL, regulates mechanosensitive flagellar motor-function., Sci Rep 7(1):5565
[3] Partridge JD., Nieto V., Harshey RM., 2015, A new player at the flagellar motor: FliL controls both motor output and bias., MBio 6(2):e02367
[4] Suzuki T., Komeda Y., 1981, Incomplete flagellar structures in Escherichia coli mutants., J Bacteriol 145(2):1036-41
[5] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.