RegulonDB RegulonDB 11.1: Gene Form
   

fucU gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

fucK fucR fucU terminator fucUp fucUp

Gene      
Name: fucU    Texpresso search in the literature
Synonym(s): ECK2799, EG10355, b2804
Genome position(nucleotides): 2938888 --> 2939310
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 48.94
External database links:  
ASAP:
 ABE-0009193
ECHOBASE:
 EB0350
ECOLIHUB:
 fucU
OU-MICROARRAY:
 b2804
STRING:
 511145.b2804
COLOMBOS: fucU


Product      
Name: L-fucose mutarotase
Synonym(s): FucU
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 15.473
Isoelectric point: 5.664
Motif(s):
 
Type Positions Sequence Comment
3 -> 139 KTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVT
22 -> 22 H UniProt: Affects slightly binding affinity toward L-fucose. Significantly reduced ribose pyranase activity..
64 -> 64 D UniProt: Affects slightly binding affinity toward L-fucose. Significantly reduced ribose pyranase activity..
106 -> 140 NRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP UniProt: In Ref. 1; CAA33129..
111 -> 111 Y UniProt: Reduces binding affinity toward L-fucose. Significantly reduced ribose pyranase activity..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0036373 - L-fucose mutarotase activity
GO:0062193 - D-ribose pyranase activity
GO:0016853 - isomerase activity
GO:0016854 - racemase and epimerase activity
GO:0016857 - racemase and epimerase activity, acting on carbohydrates and derivatives
GO:0048029 - monosaccharide binding
GO:0042802 - identical protein binding
GO:0042806 - fucose binding
biological_process GO:0005975 - carbohydrate metabolic process
GO:0005996 - monosaccharide metabolic process
GO:0006004 - fucose metabolic process
GO:0042354 - L-fucose metabolic process
GO:0036065 - fucosylation
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P0AEN8
DIP:
 DIP-47990N
ECOCYC:
 EG10355-MONOMER
ECOLIWIKI:
 b2804
INTERPRO:
 IPR023750
INTERPRO:
 IPR023751
INTERPRO:
 IPR007721
MODBASE:
 P0AEN8
PDB:
 2WCV
PFAM:
 PF05025
PRIDE:
 P0AEN8
PRODB:
 PRO_000022733
REFSEQ:
 NP_417284
SMR:
 P0AEN8
UNIPROT:
 P0AEN8


Operon      
Name: fucPIKUR         
Operon arrangement:
Transcription unit        Promoter
fucPIKUR
fucU
fucR


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FucR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB