RegulonDB RegulonDB 10.8: Gene Form
   

glpB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

glpA glpT glpB glpC rpnE GlpR Fis FNR GlpR CRP Fis GlpR FNR CRP GlpR Fis Fis GlpR CRP Fis IHF Fis IHF GlpR GlpR GlpR terminator anti-terminator anti-anti-terminator terminator yfaDp5 yfaDp5 glpABCp glpABCp glpTQp glpTQp glpQp glpQp

Gene      
Name: glpB    Texpresso search in the literature
Synonym(s): ECK2234, EG10392, b2242, psi-51
Genome position(nucleotides): 2354265 --> 2355524 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.87
External database links:  
ASAP:
 ABE-0007424
CGSC:
 17695
ECHOBASE:
 EB0387
OU-MICROARRAY:
 b2242
PortEco:
 glpB
STRING:
 511145.b2242
COLOMBOS: glpB


Product      
Name: anaerobic glycerol-3-phosphate dehydrogenase subunit B
Synonym(s): GlpB
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,inner membrane
Molecular weight: 45.357
Isoelectric point: 6.046
Motif(s):
 
Type Positions Sequence
4 -> 399 DTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELGLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGV

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.7 - anaerobic respiration
  1 - metabolism --> 1.4 - energy production/transport --> 1.4.1 - electron donors
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.6 - misc. glycerol metabolism
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0009331 - glycerol-3-phosphate dehydrogenase complex
molecular_function GO:0016491 - oxidoreductase activity
GO:0004368 - glycerol-3-phosphate dehydrogenase (quinone) activity
GO:0010181 - FMN binding
GO:0052590 - sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity
GO:0052591 - sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity
biological_process GO:0009061 - anaerobic respiration
GO:0006072 - glycerol-3-phosphate metabolic process
GO:0019563 - glycerol catabolic process
GO:0046168 - glycerol-3-phosphate catabolic process
GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-9791N
ECOCYC:
 ANGLYC3PDEHYDROGSUBUNITB-MONOMER
ECOLIWIKI:
 b2242
INTERPRO:
 IPR003953
INTERPRO:
 IPR036188
INTERPRO:
 IPR009158
MINT:
 MINT-1319997
PFAM:
 PF00890
PRIDE:
 P13033
PRODB:
 PRO_000022793
REFSEQ:
 NP_416745
SMR:
 P13033
UNIPROT:
 P13033


Operon      
Name: glpABC         
Operon arrangement:
Transcription unit        Promoter
glpABC


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FNR, FlhDC, Fis
Repressed by: ArcA, GlpR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yfaDp5 2356690 forward Similarity to the consensus
Read more > 		[ICWHO] [1]


Evidence    

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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