Gene
Name:	glpT
Synonym(s):	ECK2232, EG10401, b2240
Genome position(nucleotides):	2351016 <-- 2352374 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	52.61
External database links:

ASAP:	ABE-0007401
CGSC:	689
ECHOBASE:	EB0396
OU-MICROARRAY:	b2240
PortEco:	glpT
STRING:	511145.b2240
COLOMBOS:	glpT

Transcriptional Regulation
	Display Regulation
Activated by:	CRP, FNR, Fis
Repressed by:	IHF, GlpR

Reference(s)
[1] Argast M., Ludtke D., Silhavy TJ., Boos W., 1978, A second transport system for sn-glycerol-3-phosphate in Escherichia coli., J Bacteriol 136(3):1070-83
[2] Boos W., Hartig-Beecken I., Altendorf K., 1977, Purification and properties of a periplasmic protein related to sn-glycerol-3-phosphate transport in Escherichia coli., Eur J Biochem 72(3):571-81
[3] Cymer F., von Heijne G., 2013, Cotranslational folding of membrane proteins probed by arrest-peptide-mediated force measurements., Proc Natl Acad Sci U S A 110(36):14640-5
[4] Ehrmann M., Boos W., Ormseth E., Schweizer H., Larson TJ., 1987, Divergent transcription of the sn-glycerol-3-phosphate active transport (glpT) and anaerobic sn-glycerol-3-phosphate dehydrogenase (glpA glpC glpB) genes of Escherichia coli K-12., J Bacteriol 169(2):526-32
[5] Eiglmeier K., Boos W., Cole ST., 1987, Nucleotide sequence and transcriptional startpoint of the glpT gene of Escherichia coli: extensive sequence homology of the glycerol-3-phosphate transport protein with components of the hexose-6-phosphate transport system., Mol Microbiol 1(3):251-8
[6] Fann MC., Busch A., Maloney PC., 2003, Functional characterization of cysteine residues in GlpT, the glycerol 3-phosphate transporter of Escherichia coli., J Bacteriol 185(13):3863-70
[7] Freedberg WB., Lin EC., 1973, Three kinds of controls affecting the expression of the glp regulon in Escherichia coli., J Bacteriol 115(3):816-23
[8] Kadner RJ., Murphy GP., Stephens CM., 1992, Two mechanisms for growth inhibition by elevated transport of sugar phosphates in Escherichia coli., J Gen Microbiol 138(10):2007-14
[9] Larson TJ., Schumacher G., Boos W., 1982, Identification of the glpT-encoded sn-glycerol-3-phosphate permease of Escherichia coli, an oligomeric integral membrane protein., J Bacteriol 152(3):1008-21
[10] Larson TJ., Ye SZ., Weissenborn DL., Hoffmann HJ., Schweizer H., 1987, Purification and characterization of the repressor for the sn-glycerol 3-phosphate regulon of Escherichia coli K12., J Biol Chem 262(33):15869-74
[11] Ludtke D., Larson TJ., Beck C., Boos W., 1982, Only one gene is required for the glpT-dependent transport of sn-glycerol-3-phosphate in Escherichia coli., Mol Gen Genet 186(4):540-7
[12] Miki K., Lin EC., 1980, Use of Escherichia coli operon-fusion strains for the study of glycerol 3-phosphate transport activity., J Bacteriol 143(3):1436-43
[13] Miki K., Silhavy TJ., Andrews KJ., 1979, Resolution of glpA and glpT loci into separate operons in Escherichia coli K-12 strains., J Bacteriol 138(1):268-9
[14] Nilsson AI., Berg OG., Aspevall O., Kahlmeter G., Andersson DI., 2003, Biological costs and mechanisms of fosfomycin resistance in Escherichia coli., Antimicrob Agents Chemother 47(9):2850-8
[15] Schryvers A., Weiner JH., 1982, The anaerobic sn-glycerol-3-phosphate dehydrogenase: cloning and expression of the glpA gene of Escherichia coli and identification of the glpA products., Can J Biochem 60(3):224-31
[16] Schumacher G., Bussmann K., 1978, Cell-free synthesis of proteins related to sn-glycerol-3-phosphate transport in Escherichia coli., J Bacteriol 135(1):239-50
[17] Silhavy TJ., Hartig-Beecken I., Boos W., 1976, Periplasmic protein related to the sn-glycerol-3-phosphate transport system of Escherichia coli., J Bacteriol 126(2):951-8
[18] Yamada M., Takeda Y., Okamoto K., Hirota Y., 1982, Physical map of the nrdA-nrdB-ftsB-glpT region of the chromosomal DNA of Escherichia coli., Gene 18(3):309-18