RegulonDB RegulonDB 10.10: Gene Form
   

malP gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

malT malP malQ Mlc CRP FNR MalT MalT MalT MalT TSS_4026 TSS_4026 TSS_4025 TSS_4025 TSS_4024 TSS_4024 TSS_4023 TSS_4023 TSS_4022 TSS_4022 TSS_4021 TSS_4021 TSS_4020 TSS_4020 TSS_4019 TSS_4019 TSS_4018 (cluster) TSS_4018 (cluster) TSS_4017 TSS_4017 malTp malTp malPp malPp TSS_4014 TSS_4014 malQp malQp

Gene      
Name: malP    Texpresso search in the literature
Synonym(s): ECK3404, EG10560, b3417, blu, malA
Genome position(nucleotides): 3550080 <-- 3552473 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.3
External database links:  
ASAP:
 ABE-0011154
CGSC:
 528
ECHOBASE:
 EB0555
ECOLIHUB:
 malP
MIM:
 232600
MIM:
 232700
OU-MICROARRAY:
 b3417
STRING:
 511145.b3417
COLOMBOS: malP


Product      
Name: maltodextrin phosphorylase
Synonym(s): Blu, MalA, MalP
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 90.522
Isoelectric point: 7.41
Motif(s):
 
Type Positions Sequence
502 -> 502 E
490 -> 490 F
548 -> 548 H
499 -> 499 Q
688 -> 688 L

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  1 - metabolism --> 1.2 - degradation of macromolecules --> 1.2.4 - polysaccharides
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0102250 - linear malto-oligosaccharide phosphorylase activity
GO:0102499 - SHG alpha-glucan phosphorylase activity
GO:0003824 - catalytic activity
GO:0016757 - glycosyltransferase activity
GO:0016740 - transferase activity
GO:0004645 - 1,4-alpha-oligoglucan phosphorylase activity
GO:0008184 - glycogen phosphorylase activity
GO:0031220 - maltodextrin phosphorylase activity
GO:0030170 - pyridoxal phosphate binding
GO:0042803 - protein homodimerization activity
biological_process GO:0008152 - metabolic process
GO:0005975 - carbohydrate metabolic process
GO:0005980 - glycogen catabolic process
GO:0030980 - alpha-glucan catabolic process
External database links:  
CAZY:
 GT35
DIP:
 DIP-10146N
ECOCYC:
 MALDEXPHOSPHORYL-MONOMER
ECOLIWIKI:
 b3417
INTERPRO:
 IPR000811
INTERPRO:
 IPR011833
INTERPRO:
 IPR035090
MODBASE:
 P00490
PANTHER:
 PTHR11468
PDB:
 1E4O
PDB:
 2ASV
PDB:
 2ECP
PDB:
 2AZD
PDB:
 2AW3
PDB:
 1AHP
PDB:
 2AV6
PDB:
 1L5V
PDB:
 1L5W
PDB:
 1L6I
PDB:
 1QM5
PFAM:
 PF00343
PRIDE:
 P00490
PRODB:
 PRO_000023152
PROSITE:
 PS00102
REFSEQ:
 YP_026218
SMR:
 P00490
UNIPROT:
 P00490


Operon      
Name: malPQ         
Operon arrangement:
Transcription unit        Promoter
malQ
malPQ


Transcriptional Regulation      
Display Regulation             
Activated by: FNR, MalT


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4014 3552499 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4017 3553091 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4018 (cluster) 3553664 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4019 3553757 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4020 3553836 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4021 3553843 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4022 3554481 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4023 3554746 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4024 3555139 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4025 3555545 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4026 3555555 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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