RegulonDB RegulonDB 10.7: Gene Form
   

osmB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yciT yciH osmB RcsB osmBp1 osmBp1 TSS_1729 TSS_1729 osmBp2 osmBp2 TSS_1728 TSS_1728

Gene      
Name: osmB    Texpresso search in the literature
Synonym(s): ECK1278, EG10679, b1283
Genome position(nucleotides): 1343110 <-- 1343328 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
52.05
External database links:  
ASAP:
ABE-0004309
CGSC:
31965
ECHOBASE:
EB0673
OU-MICROARRAY:
b1283
PORTECO:
osmB
REGULONDB:
b1283
STRING:
511145.b1283
M3D: osmB
COLOMBOS: osmB
PortEco: b1283


Product      
Name: osmotically-inducible lipoprotein OsmB
Synonym(s): OsmB
Sequence: Get amino acid sequence Fasta Format
Cellular location: periplasmic space,inner membrane
Molecular weight: 6.948
Isoelectric point: 10.789
Motif(s):
 
Type Positions Sequence
34 -> 71 TAIGAGAGALGGAVLTDGSTLGTLGGAAVGGVIGHQVG
24 -> 72 CSNWSKRDRNTAIGAGAGALGGAVLTDGSTLGTLGGAAVGGVIGHQVGK
1 -> 23 MFVTSKKMTAAVLAITLAMSLSA

 

Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.5 - adaptations --> 5.5.1 - osmotic pressure
Gene Ontology Terms (GO)  
cellular_component GO:0019867 - outer membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
Note(s): Note(s): ...[more].
Reference(s): [1] Grabowicz M., et al., 2017
External database links:  
ECOCYC:
EG10679-MONOMER
ECOLIWIKI:
b1283
INTERPRO:
IPR008816
PFAM:
PF05433
PRIDE:
P0ADA7
PRODB:
PRO_000023467
PROSITE:
PS51257
PROTEINMODELPORTAL:
P0ADA7
REFSEQ:
NP_415799
UNIPROT:
P0ADA7


Operon      
Name: osmB         
Operon arrangement:
Transcription unit        Promoter
osmB
osmB


Transcriptional Regulation      
Display Regulation             
Activated by: RcsB


Regulation by small RNA    
  Display Regulation
small RNA omrA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1728 1343368 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_1729 1343371 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Grabowicz M., Silhavy TJ., 2017, Redefining the essential trafficking pathway for outer membrane lipoproteins., Proc Natl Acad Sci U S A 114(18):4769-4774

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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