RegulonDB

Gene
Name:	osmC
Synonym(s):	ECK1476, EG10680, b1482
Genome position(nucleotides):	1556625 --> 1557056 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	50.0
External database links:

ASAP:	ABE-0004944
CGSC:	32184
ECHOBASE:	EB0674
OU-MICROARRAY:	b1482
PortEco:	osmC
STRING:	511145.b1482
COLOMBOS:	osmC

Product

Name:

osmotically inducible peroxiredoxin OsmC

Synonym(s):

OsmC, osmotically inducible protein

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

15.088

Isoelectric point:

5.664

Motif(s):

Type	Positions	Sequence
	43 -> 138	EKGTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKSEVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLD
	2 -> 143	TIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEKGTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKSEVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		5 - cell processes --> 5.5 - adaptations --> 5.5.1 - osmotic pressure
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0005829 - cytosol
	molecular_function	GO:0016491 - oxidoreductase activity GO:0004601 - peroxidase activity GO:0016209 - antioxidant activity GO:0051920 - peroxiredoxin activity GO:0042803 - protein homodimerization activity
	biological_process	GO:0006979 - response to oxidative stress GO:0006972 - hyperosmotic response GO:0055114 - oxidation-reduction process GO:0033194 - response to hydroperoxide GO:0098869 - cellular oxidant detoxification

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

PDB:

PDB:

PFAM:

PRIDE:

PRODB:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

osmC

Operon arrangement:

Transcription unit	Promoter
osmC	osmCp1
osmC	osmCp2

Transcriptional Regulation
	Display Regulation
Activated by:	NhaR, Lrp, RcsB
Repressed by:	H-NS, Lrp

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_1833	1556600		forward	nd	[RS-EPT-CBR]	[1]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.