RegulonDB 8.2: Gene Form

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ppc gene in Escherichia coli K-12 genome

Gene local context to scale (view description)

Gene
Name:	ppc
Synonym(s):	asp, b3956, glu
Genome position(nucleotides):	4148470 <-- 4151121 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	55.66
External database links:

ECOCYC:	EG10756
GENBANK:	1790393
GENBANK_RefSeq:	16131794
OU-MICROARRAY:	b3956
M3D:	ppc
PortEco:	b3956

Product

Name:

Ppc

Synonym(s):

Asp, Glu

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

99.062

Isoelectric point:

5.4

Motif(s):

Type	Positions	Sequence
	587 -> 587	R
	579 -> 579	H
	138 -> 138	H

Classification:

metabolism --> energy metabolism, carbon --> TCA cycle

Note(s):

Note(s): ...[more].

External database links:

ECOCYC:

EXPASY:

GENPROTEC:

GO:

PDB:

PDB:

Operon

Name:

ppc

Operon arrangement:

Transcription unit	Promoter
ppc	ppcp

Transcriptional Regulation
	Display Regulation
	Note: The TF binding sites with unknown position are not displayed in the graphic.
Repressed by:	Cra

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_4279	4149091	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4280 (cluster)	4149702	reverse	For this promoter, there is a cluster of 2 transcription start sites,in the interval 4149701 to 4149702, where the highest frequency is at position 4149701. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[1]
promoter	TSS_4281	4149707	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4282	4149709	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4283	4149717	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4284	4149721	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4285	4149740	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4286	4149917	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4287	4149926	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4288 (cluster)	4149941	reverse	For this promoter, there is a cluster of 3 transcription start sites,in the interval 4149939 to 4149941, where the highest frequency is at position 4149940. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[1]
promoter	TSS_4289 (cluster)	4149945	reverse	For this promoter, there is a cluster of 3 transcription start sites,in the interval 4149943 to 4149945, where the highest frequency is at position 4149945. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[1]
promoter	TSS_4290	4150069	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4291	4150072	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4292	4150076	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4293	4150083	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4294	4150108	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4295	4150172	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4296	4150176	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4297	4150181	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4298	4150187	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4299	4150466	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4300	4150551	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4301 (cluster)	4150699	reverse	For this promoter, there is a cluster of 3 transcription start sites,in the interval 4150697 to 4150699, where the highest frequency is at position 4150698. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[1]
promoter	TSS_4302	4150937	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4303	4151144	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4304 (cluster)	4151211	reverse	For this promoter, there is a cluster of 3 transcription start sites,in the interval 4151209 to 4151211, where the highest frequency is at position 4151210. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[1]
promoter	TSS_4305	4151595	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4306	4151598	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4307	4151717	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4308	4151720	reverse	nd	[RS-EPT-CBR]	[1]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Mu¿¿iz-Rascado L, Garc¿¿a-Sotelo JS, Weiss V, Solano-Lira H, Mart¿¿nez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hern¿¿ndez S, Alquicira-Hern¿¿ndez K, L¿¿pez-Fuentes A, Porr¿¿n-Sotelo L, Huerta AM, Bonavides-Mart¿¿nez C, Balderas-Mart¿¿nez YI, Pannier L, Olvera M, Labastida A, Jim¿¿nez-Jacinto V, Vega-Alvarado L, Del Moral-Ch¿¿vez V, Hern¿¿ndez-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Mu¿¿iz-Rascado L, Garc¿¿a-Sotelo JS, Weiss V, Solano-Lira H, Mart¿¿nez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hern¿¿ndez S, Alquicira-Hern¿¿ndez K, L¿¿pez-Fuentes A, Porr¿¿n-Sotelo L, Huerta AM, Bonavides-Mart¿¿nez C, Balderas-Mart¿¿nez YI, Pannier L, Olvera M, Labastida A, Jim¿¿nez-Jacinto V, Vega-Alvarado L, Del Moral-Ch¿¿vez V, Hern¿¿ndez-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.