RegulonDB RegulonDB 10.6.3: Gene Form
   

recF gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gyrB dnaA dnaN recF Fis Fis dnaNp1 dnaNp1 TSS_4269 TSS_4269 dnaNp2 dnaNp2 dnaNp3 dnaNp3 TSS_4268 TSS_4268 TSS_4267 TSS_4267 dnaNp4 dnaNp4 recFp2 recFp2 recFp1 recFp1 TSS_4265 (cluster) TSS_4265 (cluster) gyrBp gyrBp TSS_4264 TSS_4264 TSS_4263 TSS_4263 TSS_4262 TSS_4262 TSS_4261 TSS_4261 TSS_4260 (cluster) TSS_4260 (cluster) TSS_4259 TSS_4259

Gene      
Name: recF    Texpresso search in the literature
Synonym(s): ECK3692, EG10828, b3700, uvrF
Genome position(nucleotides): 3880148 <-- 3881221 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.03
External database links:  
ASAP:
ABE-0012095
CGSC:
308
ECHOBASE:
EB0821
ECOCYC:
EG10828
ECOLIHUB:
recF
OU-MICROARRAY:
b3700
REGULONDB:
b3700
STRING:
511145.b3700
M3D: recF
COLOMBOS: recF
PortEco: b3700


Product      
Name: DNA repair protein RecF
Synonym(s): RecF, UvrF
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 40.514
Isoelectric point: 7.293
Motif(s):
 
Type Positions Sequence
36 -> 36 K
3 -> 354 LTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGK
30 -> 37 GANGSGKT
2 -> 357 SLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD

 

Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.1 - DNA related --> 2.1.1 - DNA replication
  2 - information transfer --> 2.1 - DNA related --> 2.1.3 - DNA recombination
  2 - information transfer --> 2.1 - DNA related --> 2.1.4 - DNA repair
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003677 - DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005515 - protein binding
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
biological_process GO:0006260 - DNA replication
GO:0006281 - DNA repair
GO:0006974 - cellular response to DNA damage stimulus
GO:0009432 - SOS response
GO:0009314 - response to radiation
GO:0009411 - response to UV
GO:0006302 - double-strand break repair
GO:0000731 - DNA synthesis involved in DNA repair
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-36037N
ECOCYC:
EG10828-MONOMER
ECOLIWIKI:
b3700
INTERPRO:
IPR027417
INTERPRO:
IPR018078
INTERPRO:
IPR001238
INTERPRO:
IPR003395
MINT:
MINT-1291712
PANTHER:
PTHR32182:SF0
PFAM:
PF02463
PRIDE:
P0A7H0
PRODB:
PRO_000023701
PROSITE:
PS00618
PROSITE:
PS00617
PROTEINMODELPORTAL:
P0A7H0
REFSEQ:
NP_418155
SMR:
P0A7H0
UNIPROT:
P0A7H0


Operon      
Name: dnaAN-recF         
Operon arrangement:
Transcription unit        Promoter
recF
recF
dnaN-recF
dnaN-recF
dnaN-recF
dnaN-recF
dnaAN-recF
dnaAN-recF


Transcriptional Regulation      
Display Regulation             
Activated by: ArgP, DnaA
Repressed by: DnaA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4259 3878251 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4260 (cluster) 3878769 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter TSS_4261 3878772 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4262 3879127 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4263 3879564 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4264 3880140 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4265 (cluster) 3880152 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter TSS_4267 3882351 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4268 3882359 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4269 3882731 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Mu¿¿iz-Rascado L, Garc¿¿a-Sotelo JS, Weiss V, Solano-Lira H, Mart¿¿nez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hern¿¿ndez S, Alquicira-Hern¿¿ndez K, L¿¿pez-Fuentes A, Porr¿¿n-Sotelo L, Huerta AM, Bonavides-Mart¿¿nez C, Balderas-Mart¿¿nez YI, Pannier L, Olvera M, Labastida A, Jim¿¿nez-Jacinto V, Vega-Alvarado L, Del Moral-Ch¿¿vez V, Hern¿¿ndez-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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